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Top news stories for the week 44

Monday, Oct 28

Researchers identify previously unknown pathway that allows cancer to grow unchecked

A new study from MUSC Hollings Cancer Center researchers shows, for the first time, that a receptor called PPAR δ, or peroxisome proliferator-activated receptor delta, is an important player in a pathway that disables the ...

Oct 28, 2024

0

126

Scientists can reverse brain aging in fruit flies by preventing buildup of a common protein

Humans aren't the only ones who grow forgetful as they age—fruit flies do, too. But because fruit flies have a lifespan of only about two months, they can be a useful model for understanding the cognitive decline that comes ...

Oct 28, 2024

0

122

1 million+ patients lose coverage as insurers, hospitals drop Medicare Advantage

Libby and Andrew Potter usually ignore the avalanche of Medicare Advantage ads that land in the mailbox at their home in Huntsville, Alabama, each fall as Medicare's open enrollment period begins.

Oct 28, 2024

0

111

Studies pinpoint immune cells and proteins linked to long COVID

Researchers at the University of Alberta have pinpointed two proteins that could serve as markers for identifying patients with long COVID—a discovery that may lead to treatments that will bring better quality of life for ...

Oct 28, 2024

0

106

New miRNA inhibitor could extinguish the 'inflammatory fire' that stroke causes in the brain

It's been more than three decades, but still there are only two treatments for a stroke: either rapid use of a clot-busting medication called tPA or surgical removal of a clot from the brain with mechanical thrombectomy. ...

Oct 28, 2024

0

97

Off-label glucose-lowering drugs may put type 1 diabetes patients at risk

A collaboration of researchers led by Emory University Rollins School of Public Health, Atlanta, is urging caution when prescribing off-label glucose-lowering drugs to individuals with type 1 diabetes (T1D).

Oct 28, 2024 report

0

94

Don't skip colonoscopy for new blood-based colon cancer screening, study says

Newly available blood tests to screen for colorectal cancer sound far more appealing than a standard colonoscopy. Instead of clearing your bowels and undergoing an invasive procedure, the tests require only a simple blood ...

Oct 28, 2024

0

77

Tuesday, Oct 29

Highly detailed reconstruction of human brain connectivity includes dozens of brainstem nuclei

Recent technological advances are allowing neuroscientists to map the human brain with increasing precision, highlighting connections between different regions and their function in greater depth. While the role of many brain ...

Oct 29, 2024 feature

0

156

Smell loss is linked to more than 100 diseases in new study

Researchers from the Charlie Dunlop School of Biological Sciences, in collaboration with The Oxford Research Centre in the Humanities, reveal a powerful link between olfactory loss and inflammation in a staggering 139 medical ...

Oct 29, 2024

0

107

Cannabis use linked to brain changes, but causality unclear

Lifetime cannabis use is associated with several changes in brain structure and function in later life, suggests an observational study, but these associations may not be causal, finds a genetic analysis of the same data, ...

Oct 29, 2024

0

85

RSV vaccines are effective, but researchers say more people need to get them

Since their introduction last year, researchers have been monitoring the real-world impact of the new respiratory syncytial virus (RSV) vaccines. In a recent commentary published in The Lancet, Angela Branche, MD, an infectious ...

Oct 29, 2024

1

81

Psilocybin shows promise as new treatment for OCD and Tourette's syndrome, finds study

A study, published in Molecular Psychiatry, led by Prof. Bernard Lerer from the Department of Psychiatry at the Hadassah—Hebrew University Medical Center shows promising results for using psilocybin, a psychedelic compound, ...

Oct 29, 2024

0

59

New research finds that subtle eye movements optimize vision

Our ability to see starts with the light-sensitive photoreceptor cells in our eyes. A specific region of the retina, termed fovea, is responsible for sharp vision. Here, the color-sensitive cone photoreceptors allow us to ...

Oct 29, 2024

0

52

Computational tool can assess immunotherapy outcomes for patients with metastatic breast cancer

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast ...

Oct 29, 2024

0

44

Wednesday, Oct 30

Electric fans fail to lower core body temperature of seniors during heat waves, study finds

A team of physiologists at the University of Ottawa's Human and Environmental Physiology Research Unit reports that use of an electric fan during periods of high temperatures by older people does not lower core body temperatures. ...

Oct 30, 2024 report

0

146

Silent intruder: How the cold sore virus maps its way through the brain

Herpes simplex virus type 1 (HSV-1), the cause of the common cold sore, can spread into the central nervous system and preferences for certain parts of the brain. Study results published today in the Journal of Virology are ...

Oct 30, 2024

0

70

Sex-specific heart attack risk factors linked to circulating proteins

Uppsala University and Karolinska Institutet researchers have identified 45 proteins in the blood that are associated with the risk of myocardial infarction (MI), commonly known as a heart attack.

Oct 30, 2024 report

0

67

Harnessing the brain's ability to suppress inappropriate immune responses may offer improved treatment

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue.

Oct 30, 2024

0

64

Researchers discover cancer mechanism that can eliminate tumors—even those resistant to immunotherapy

A technological breakthrough by medical researchers at Tel Aviv University enabled the discovery of a cancer mechanism that prevents the immune system from attacking tumors. The researchers were surprised to find that reversing ...

Oct 30, 2024

0

62

Smart sensor patch detects health symptoms through edge computing

Edge computing on a smartphone has been used to analyze data collected by a multimodal flexible wearable sensor patch and detect arrhythmia, coughs and falls.

Oct 30, 2024

0

48

New voltage indicator enables ultra-sensitive synaptic imaging

Bioengineers and neuroscientists at the Wu Tsai Neurosciences Institute at Stanford University have developed a highly sensitive tool for detecting brain cells' subtlest electrical signals.

Oct 30, 2024

0

33

Thursday, Oct 31

Vitamin K₂ reduces dreaded nighttime leg cramps in clinical trial

They strike in the middle of the night without warning. A painful contraction of the calf muscle wrenches sleepers out of dreamland and throws them into a Greco-Roman wrestling match with an unseen opponent. The dreaded leg ...

Oct 31, 2024 report

0

216

Human proteins may explain inter-individual differences in functional brain connectivity, research suggests

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale.

Oct 31, 2024

0

91

Subcellular 'wearable' devices that wrap around neurons could measure and modulate electrical activity

Wearable devices like smartwatches and fitness trackers interact with parts of our bodies to measure and learn from internal processes, such as our heart rate or sleep stages.

Oct 31, 2024

0

69

Computer game study reveals an association between autistic traits and successful exploration strategies

People with stronger autistic trails showed distinct exploration patterns and higher levels of persistence in a computer game, ultimately resulting in better performance than people with lower scores of autistic traits, according ...

Oct 31, 2024

0

68

New model uses infection 'signatures' to predict who lives or dies of COVID-19

A critical challenge during the early COVID-19 pandemic was determining whether a patient would survive the infection or die from it. And even though a host of lifesaving therapeutics now spares substantially more lives than ...

Oct 31, 2024 feature

0

62

Researchers solve medical mystery of neurological symptoms in kids

Most people who visit a doctor when they feel unwell seek a diagnosis and a treatment plan. But for some 30 million Americans with rare diseases, their symptoms don't match well-known disease patterns, sending families on ...

Oct 31, 2024

0

55

Personalized medicine research offers fast, cost-effective method to match cancer drugs to patients

In a major leap toward more effective cancer treatments, researchers at the University of Oulu have developed an innovative pipeline designed to directly analyze drug responses in primary patient tumor samples.

Oct 31, 2024

0

54

Friday, Nov 01

Scientists successfully reverse liver fibrosis in mice

Cirrhosis, hepatitis infection and other causes can trigger liver fibrosis—a potentially lethal stiffening of tissue that, once begun, is irreversible. For many patients, a liver transplant is their only hope. However, ...

Nov 1, 2024

0

114

Precision diagnostics close in on Parkinson's disease proteins in extracellular vesicles

Brain disorders like Parkinson's disease (PD) or Alzheimer's disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even ...

Nov 1, 2024

0

96

Prolonged sitting can sabotage health, even if you're young and exercise

Between long commutes, Zoom-packed workdays and evenings of streaming and scrolling, Millennials now spend more than 60 hours per week sitting, potentially boosting their heart disease risk and accelerating other signs of ...

Nov 1, 2024

0

84

Study shows how education, occupation and wealth affect the risk of cognitive impairment

Socioeconomic factors such as education, occupation, and wealth influence the likelihood of developing cognitive impairment or dementia in later life and whether a person is likely to recover, finds a new study led by UCL ...

Nov 1, 2024

0

80

New Huntington's treatment prevents protein aggregation

Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the ...

Nov 1, 2024

0

57

AI model predicts progression of breast cancer better than standard hospital tests, study claims

A team of AI and medical researchers at startup Ataraxis AI, who are also affiliated with a host of institutions across the U.S., has announced the development of an AI model that they claim is more accurate at predicting ...

Nov 1, 2024 report

0

43

Enzymes linked to high-fat diet's impact on multiple sclerosis offer potential way to protect neurons

Research published in the journal Glia has identified crucial links between dietary choices and the progression of multiple sclerosis (MS).

Nov 1, 2024

0

41

Saturday, Nov 02

Insulin resistance caused by sympathetic nervous system over-activation, a paradigm-shifting study finds

Rutgers Robert Wood Johnson Medical School and collaborating institutions have found that overnutrition leads to insulin resistance and metabolic disorders through increased activity of the sympathetic nervous system (SNS). ...

Nov 2, 2024 report

2

147

Novel visualization method helps make sense of large neuronal activity datasets

Recent technological advances opened exciting possibilities for neuroscience, enabling the collection of increasingly detailed neural data. Making sense of the large number of neural recordings gathered by neuroscientists ...

Nov 2, 2024 feature

0

52

Can a mammogram identify heart disease risk?

When people check in for their annual mammogram these days, some may face a surprising question: In addition to reviewing the mammogram for breast cancer, would the patient like the radiologist to examine the images for heart ...

Nov 2, 2024

0

1

The four types of systemic therapy for breast cancer

Treatment for breast cancer can come in many forms. In addition to surgery to remove cancerous tissue and radiation therapy, breast cancer is also commonly treated with drugs that are taken orally or intravenously, as an ...

Nov 2, 2024

0

0

Expert explains cardiac amyloidosis

Cardiac amyloidosis is a rare condition defined by the abnormal production of proteins that bind together to form amyloid proteins. These amyloids can gather in different organs throughout the body, including the heart, liver ...

Nov 2, 2024

0

0

Researchers shed light on increased rates of severe human infections caused by Streptococcus subspecies

A concerning increase in global rates of severe invasive infections becoming resistant to key antibiotics has a team of infectious disease researchers at the Houston Methodist Research Institute studying a recently emerged ...

Nov 2, 2024

0

0

Daylight saving time ends Sunday. Time to 'fall back' an hour

The good news: You will get a glorious extra hour of sleep. The bad: It'll be dark as a pocket by late afternoon for the next few months in the U.S.

Nov 2, 2024

0

0

Sunday, Nov 03

Preventing obesity in very young children could be in the palm of parents' hands

A study co-led by a Johns Hopkins Children's Center clinician-researcher shows that adding text messaging and other electronic feedback to traditional in-clinic health counseling for parents about feeding habits, playtime ...

Nov 3, 2024

0

46

Warning for younger women: Be vigilant on breast cancer risk

Breast cancer rates rose by 1% a year from 2012–2021 for all American women combined, but steeper increases were seen for women under 50 and Asian American and Pacific Islander women, according to the American Cancer Society, ...

Nov 3, 2024

0

0

Mpox cases in Congo may be stabilizing. Experts say more vaccines are needed to stamp out virus

Some health officials say mpox cases in Congo appear to be "stabilizing"—a possible sign that the main epidemic for which the World Health Organization made a global emergency declaration in August might be on the decline.

Nov 3, 2024

0

0

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