Leukemia
Unraveling why children with Down syndrome have increased leukemia risk
Children with Down syndrome (DS) have an increased risk of developing leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (ALL). Through their studies in a mouse model of DS, a ...
Genetics
Feb 22, 2012 |
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Targeted drug helps leukemia patients who do not benefit from initial therapy
A new study has found that patients with chronic myeloid leukemia (CML) who have not responded to interferon treatments experience long-term benefits when they switch to the targeted drug imatinib. Published early online ...
Cancer
Feb 27, 2012 |
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Genetic profiling helps doctors more accurately predict prognosis, guide treatment decisions for leukemia patients
Researchers have identified a set of genetic abnormalities in patients with acute myelogenous leukemia (AML) that doctors can use to more accurately predict patients' prognoses and select treatments that are most likely to ...
Cancer
Mar 14, 2012 |
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Study finds genes improving survival with higher chemo doses in leukemia
New research published in the March 15 issue of the New England Journal of Medicine identifies gene mutations associated with improved overall survival with higher doses of chemotherapy for patients with acute myeloid leukem ...
Cancer
Mar 14, 2012 |
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Identifying acute myeloid leukemia gene mutations may indicate risk, best treatment
An international group of researchers, including those from Moffitt Cancer Center in Tampa, Fla., have published a paper in the March 14 issue of the New England Journal of Medicine reviewing the results of a study that a ...
Cancer
Mar 23, 2012 |
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'Druggable' protein complex identified as a therapeutic target in acute myeloid leukemia
Scientists at Cold Spring Harbor Laboratory have identified a candidate drug target for treating acute myeloid leukemia (AML), a white blood cell cancer that proliferates out of control in the bone marrow. The team, led by ...
Cancer
Apr 02, 2012 |
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FLT3 gene mutations play critically important role in acute myeloid leukemia
The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) ...
Cancer
Apr 15, 2012 |
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Study identifies potential treatment for lethal childhood leukemia
Columbia University Medical Center (CUMC) scientists have demonstrated that two related enzymes — phosphoinositide-3 kinase (PI3K) gamma and delta — play a key role in the development of T-cell acute lymphoblastic ...
Cancer
Apr 16, 2012 |
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New biomarker may predict prognosis for patients with chronic lymphocytic leukemia
Researchers at the University of California-San Diego School of Medicine have shown that G protein-coupled receptor expression may predict the prognosis of patients with chronic lymphocytic leukemia. Their findings may identify ...
Cancer
Apr 24, 2012 |
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A microRNA prognostic marker identified in acute leukemia
A study has identified microRNA-3151 as a new independent prognostic marker in certain patients with acute leukemia. The study involves patients with acute myeloid leukemia and normal-looking chromosomes (CN-AML).
Cancer
May 14, 2012 |
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Experimental agent may help older people with chronic leukemia
The experimental drug ibrutinib (PCI-32765) shows great promise for the treatment of elderly patients with chronic lymphocytic leukemia (CLL), according to interim findings from a clinical trial.
Cancer
May 16, 2012 |
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Inherited DNA change explains overactive leukemia gene
A small inherited change in DNA is largely responsible for overactivating a gene linked to poor treatment response in people with acute leukemia.
Genetics
May 25, 2012 |
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Why chemotherapy fails: Scientists show why leukemia often returns
The fight against cancer is not won in a single battle: Long after a cancer has been beaten into remission, it can return. The reason for this is under debate, and much is unclear. New research led by Weizmann Institute scientists ...
Cancer
May 29, 2012 |
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Tumor cells' inner workings predict cancer progression
Using a new assay method to study tumor cells, researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center have found evidence of clonal evolution in chronic ...
Cancer
Jul 27, 2012 |
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Gene discovery could improve treatment for acute myeloid leukemia
Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a ...
Cancer
Aug 13, 2012 |
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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.
In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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