Melanoma

Predicting cancer's next move

Research led by Broad senior associate member Levi Garraway and published this week in Nature offers a new approach to studying drug resistance in cancer. The approach helped them identify which biological pathwa ...

Nov 11, 2013
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Blood test reveals skin cancer spread

A simple blood test could be used to identify patients whose melanoma – the most serious form of skin cancer – has started to spread to other parts of the body, according to research presented at the ...

Nov 04, 2013
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New biomarker may help guide treatment of melanoma patients

A functional biomarker that can predict whether BRAF-mutant melanomas respond to drugs targeting BRAF could help guide the treatment of patients with these cancers, according to results presented here at the AACR-NCI-EORTC ...

Oct 22, 2013
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Cutting off all points of escape for melanoma cells

Despite the success of recent approved therapeutics to treat advanced melanoma, metastatic cancer cells inevitably evolve resistance to drugs. In the journal Cell Reports, a team of researchers based at The Wistar Instit ...

Sep 19, 2013
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Team finds new target for melanoma treatment

Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) today announced the discovery that a gene encoding an enzyme, phosphoinositide-dependent kinase-1 (PDK1), plays an essential role in the development ...

Sep 16, 2013
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Scientists identify targets for melanoma immunotherapy

Using a highly sensitive technology called NanoString, researchers have identified seven targets that could potentially be used to develop new immunotherapies for patients with metastatic melanoma, according to a study published ...

Sep 10, 2013
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Latest Spotlight News

New research characterizes in-flight pediatric deaths

In a first-of-its-kind study, researchers at University Hospitals Rainbow Babies & Children's Hospital (UH Rainbow) found that lap infants may be at greater risk for death on a commercial airline flight. The study analyzed ...

Ibuprofen relieves women's hurt feelings, not men's

(Medical Xpress)—For years, researchers have known that physical pain relievers such as ibuprofen can also help ease emotional pain, but new research suggests that ibuprofen has contrasting effects on men ...

Brain tumour cells found circulating in blood

(Medical Xpress)—German scientists have discovered rogue brain tumour cells in patient blood samples, challenging the idea that this type of cancer doesn't generally spread beyond the brain.

Computer model reveals cancer's energy source

(Medical Xpress)—A computer model study reveals – for the first time – details of an energy-creating process vital and unique to cancer cells. The research holds promise for new interventions and for ...

Small RNAs in blood may reveal heart injury

(Medical Xpress)—Like clues to a crime, specific molecules in the body can hint at exposure to toxins, infectious agents or even trauma, and so help doctors determine whether and how to treat a patient. ...

Researchers uncover clues to flu's mechanisms

A flu virus acts like a Trojan horse as it attacks and infects host cells. Scientists at Rice University and Baylor College of Medicine have acquired a clearer view of the well-hidden mechanism involved.