Melanoma

Transcription factors regulating blood oxygen linked to melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.

Cancer created Apr 16, 2013 | popularity not rated yet | comments 0 | with audio podcast

Food dye could provide 'blueprint' for treatment of Panx1-related diseases

The food dye Brilliant Blue FCF (BB FCF) could be a useful tool in the development of treatments for a variety of conditions involving the membrane channel protein Pannexin 1(Panx1), according to a study in The Journal of General Physi ...

Medical research created Apr 29, 2013 | popularity not rated yet | comments 0

Taking omega-3 supplements may help prevent skin cancer, new study finds

(Medical Xpress)—Taking omega-3 fish oils could help to protect against skin cancer, according to researchers at The University of Manchester. The team has just carried out the first clinical trial to examine the impact ...

Cancer created Feb 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

In-transit melanoma advance is difficult to predict

(HealthDay)—Progressive disease cannot be reliably predicted by patient, clinical, or procedural factors in patients receiving regional therapy for advanced melanoma of the extremities, according to a study ...

Surgery created Apr 15, 2013 | popularity not rated yet | comments 0

New drug shrinks brain tumours in melanoma patients

(Medical Xpress)—Australian researchers have given hope to patients with advanced melanoma by showing that a new drug targeting a common mutation in melanoma successfully shrank tumours that had spread to the brain.

Cancer created Oct 08, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find cause of chemotherapy resistance in melanoma

Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.

Cancer created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Immune system can use melanoma's own proteins to kill off cancer cells

Though a small group of proteins, the family called Ras controls a large number of cellular functions, including cell growth, differentiation, and survival. And because the protein has a hand in cellular division, mutated ...

Cancer created Feb 04, 2013 | popularity not rated yet | comments 0 | with audio podcast

Hope in stopping melanoma from spreading: Study shows that inhibiting key protein prevents metastasis to lungs in mice

(Medical Xpress)—Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer. Inhibition of the protein known as adenosine diphosphate ribosylation ...

Cancer created Mar 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Heart-healthy lifestyle also reduces cancer risk

Following the American Heart Association's Life's Simple 7 steps to reduce your risk for heart disease can also help prevent cancer, according to new research in the American Heart Association journal Circulation.

Cancer created Mar 18, 2013 | popularity 5 / 5 (1) | comments 0

Naturally occurring substance proves effective against deadly skin cancer in laboratory tests

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Mining information contained in clinical notes could yield early signs of harmful drug reactions

Mining the records of routine interactions between patients and their care providers can detect drug side effects a couple of years before an official alert from the U.S. Food and Drug Administration, a Stanford University ...

Medications created Apr 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

New melanoma drug Zelboraf nearly doubles survival in majority of patients

Investigators from Vanderbilt-Ingram Cancer Center (VICC) and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.

Cancer created Feb 22, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Tumors deliberately create conditions that inhibit body's best immune response

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune respon ...

Cancer created Mar 01, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Fighting melanoma's attraction to the brain

(Medical Xpress)—The process of metastasis, by which cancer cells travel from a tumor site and proliferate at other sites in the body, is a serious threat to cancer patients. According to the National Cancer ...

Cancer created Sep 19, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists find molecular switch that allows melanoma to resist therapy

The National Cancer Institute (NCI) estimates that as many as one in 51 men and women will be diagnosed with melanoma—the deadliest form of skin cancer—at some point during their lifetimes. A research ...

Genetics created Feb 02, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast


Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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