Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for ...
Jan 12, 2021
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Ultraviolet radiation can cause a rare type of eye cancer, conjunctival melanoma, according to research funded by Cancer Research UK and others and published in Nature Communications today.
Jan 11, 2021
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In their move to circumvent the immune system, melanoma cells end up with a deficiency of the crucial nutrient tryptophan. Unlike healthy cells, these cancer cells can continue to synthesize proteins to survive, but this ...
Dec 17, 2020
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A vaccine created to prevent the recurrence of the deadly skin cancer melanoma is about twice as effective when patients also receive two components that boost the number and effectiveness of immune system cells called dendritic ...
Nov 16, 2020
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A new study led by researchers at the University of Kentucky Markey Cancer Center and UK Department of Pharmacology and Nutritional Sciences demonstrates the potential benefit of using an anti-leukemic drug nilotinib—most ...
Oct 30, 2020
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Research led by Queen Mary University of London has revealed novel insights into the mechanisms employed by melanoma cells to form tumors at secondary sites around the body. The findings from the study may help to identify ...
Oct 20, 2020
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The sophisticated human immune system has evolved to become an effective protection system against a great number of diseases, including cancer. The immune system recognizes and destroys cancer cells using a monitoring process ...
Oct 19, 2020
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Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UC San Francisco scientist who led a new study to detect DNA mutations in individual skin cells.
Oct 7, 2020
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...
Jul 8, 2020
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As COVID-19 restrictions loosen this summer, Canadians will spend more time outdoors and make the most of the sunshine. A new study from McGill University suggests why men may be more genetically prone to develop skin cancer.
Jun 23, 2020
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