Ovarian Cancer

Study drug is first to help patients with recurrent low-grade ovarian cancer

Low-grade serous ovarian cancer is less common and aggressive than the high-grade variety, yet exceptionally difficult to treat when frontline therapy fails.

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Study prompts rethink of how ovaries develop

(Medical Xpress)—New research from the University of Adelaide will rewrite the text books on how an ovary is formed, as well as providing new insights into women's health and fertility.

Medical research created Feb 08, 2013 | popularity not rated yet | comments 0 | with audio podcast

Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...

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Early menopause may occur in women with BRCA gene, study finds

Women with harmful mutations in the BRCA gene, which put them at higher risk of developing breast and ovarian cancer, tend to undergo menopause significantly sooner than other women, allowing them an even ...

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DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

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New test predicted presence of harmful BRCA mutations

A new multiple gene expression profile test was able to predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a jour ...

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Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

Cancer created Jan 10, 2013 | popularity 4.5 / 5 (6) | comments 0 | with audio podcast

Scientists use Pap test fluid to detect ovarian, endometrial cancers

Using cervical fluid obtained during routine Pap tests, scientists at the Johns Hopkins Kimmel Cancer Center have developed a test to detect ovarian and endometrial cancers. In a pilot study, the "PapGene" test, which relies ...

Cancer created Jan 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Ovarian cancer stem cell study puts targeted therapies within reach

Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer ...

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Scientists discover gene linked to breast and ovarian cancer

(Medical Xpress)—A team of researchers led by the Institute of Cancer Research, London, have found that rare mutations in a gene called PPM1D are linked to an increased risk of breast and ovarian cancer. The mutations are ...

Cancer created Dec 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study uncovers mechanism used by BRCA1 to suppress tumors

A new study by Georgetown University Medical Center researchers reveals how a well-known tumor suppressor gene may be functioning to stop cancer cell growth.

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Research identifies targeted molecular therapy for untreatable NF1 tumors

Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1).

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Ovarian cancer patients have lower mortality rates when treated at high-volume hospitals

A study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) at NewYork-Presbyterian/Columbia University Medical Center, recently e-published ahead of print by the Journal of Clinical Oncology, sugges ...

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Researchers reveal how Trop2 protein drives tumor growth in prostate, other epithelial cancers

(Medical Xpress)—Researchers led by Tanya Stoyanova and Dr. Owen Witte of UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have determined how a protein known as Trop2 drives the growth ...

Cancer created Oct 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

Blood cells may offer telltale clues in cancer diagnosis

Postdoctoral Research Fellow Devin Koestler is a biostatistician in the Geisel School of Medicine at Dartmouth. He develops and applies statistical methods to large volumes of data, seeking new approaches ...

Cancer created Oct 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast


Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses.

Most (more than 90%) ovarian cancers are classified as "epithelial" and are believed to arise from the surface (epithelium) of the ovary. However, some evidence suggests that the fallopian tube could also be the source of some ovarian cancers. Since the ovaries and tubes are closely related to each other, it is thought that these fallopian cancer cells can mimic ovarian cancer. Other types may arise from the egg cells (germ cell tumor) or supporting cells. These cancers are grouped into the category of gynecologic cancer.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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