Genetics

How genetic mutations promote Ewing's sarcoma

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have elucidated at the molecular level how an otherwise innocuous inherited mutation that is quite common in European populations interacts with a spontaneous ...

Jul 28, 2015
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Human disease epigenomics 2.0

The study of how genes are regulated and how their regulation affects human disease has the potential to generate insights into mechanisms that aren't based on variation in DNA sequence, and could even show that temporally ...

Jul 08, 2015
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Novel approach identifies unique DNA signature

Researchers in Keele University's Research Institute for Science and Technology in Medicine and at the Haywood Rheumatology Centre, in Staffordshire, UK, and the University Hospitals of North Midlands NHS Trust, have for ...

Jul 15, 2015
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A glimmer of hope for patients with leukodystrophies

Leukodystrophies are deadly neurodegenerative diseases that affect one in 7,000 children and remain incurable. These genetic diseases attack myelin or the "insulating rubber sheath" surrounding neurons, which leads to deteriorating ...

Jul 08, 2015
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IGF2 variant affects prenatal and postnatal growth

(HealthDay)—An IGF2 variant (c.191C—>A, p.Ser64Ter) affects postnatal as well as prenatal growth among those who have inherited the variant through paternal transmission, according to a report published online July 8 ...

Jul 09, 2015
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Extra DNA acts as a 'spare tire' for our genomes

Carrying around a spare tire is a good thing—you never know when you'll get a flat. Turns out we're all carrying around "spare tires" in our genomes, too. Today, in ACS Central Science, researchers report that an extra ...

Jul 06, 2015
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