PLoS Computational Biology
PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
Hallmarks of psychiatric illness can reveal themselves remotely
Researchers discovered that healthy people and those with borderline personality disorder displayed different patterns of behavior while playing an online strategy game, so much so that when healthy players ...
Psychology & Psychiatry
Apr 09, 2013 |
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New method identifies genes that can predict prognoses of cancer patients
In recent years, it has been thought that select sets of genes might reveal cancer patients' prognoses. However, a study published last year examining breast cancer cases found that most of these "prognostic signatures" were ...
Genetics
Jan 25, 2013 |
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Wild animals may contribute to the resurgence of African sleeping sickness
Wild animals may be a key contributor to the continuing spread of African sleeping sickness, new research published in PLOS Computational Biology shows. The West African form of the disease, also known as Gambiense Human ...
Diseases, Conditions, Syndromes
Jan 17, 2013 |
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Computer model enables better understanding of what happens during and after stroke
(Medical Xpress)—At the moment that someone is suffering a stroke, the immediate concern is getting them stabilized. Once the initial attack has passed, additional treatment and preventive measures can ...
Medical research
Nov 27, 2012 |
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Privacy vs. protection: Study considers how to manage epidemics in information blackouts
When foot-and-mouth disease swept through the British countryside in early 2001, more than 10 million sheep, cattle and pigs were slaughtered to control the disease. Despite the devastation, the disease was contained within ...
Diseases, Conditions, Syndromes
Nov 01, 2012 |
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The brain's circuit diagram: New method facilitates the mapping of connections between neurons
(Medical Xpress)—The human brain accomplishes its remarkable feats through the interplay of an unimaginable number of neurons that are interconnected in complex networks. A team of scientists has now developed ...
Neuroscience
Oct 18, 2012 |
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Stress breaks loops that hold short-term memory together: study
Stress has long been pegged as the enemy of attention, disrupting focus and doing substantial damage to working memory—the short-term juggling of information that allows us to do all the little things that make us productive.
Neuroscience
Sep 13, 2012 |
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Is too much brain activity connected to Alzheimer's disease?
High baseline levels of neuronal activity in the best connected parts of the brain may play an important role in the development of Alzheimer's disease. This is the main conclusion of a new study appearing in PLoS Computational Bi ...
Alzheimer's disease & dementia
Aug 16, 2012 |
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New statistical method provides way to analyze synchronized neural activity in animals
Researchers from the RIKEN Brain Science Institute have developed a new method of statistical analysis that can estimate the extent to which the activity of multiple neurons is group-wise synchronized.
Neuroscience
Aug 03, 2012 |
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Both innate and adaptive immune responses are critical to the control of influenza
Both innate and adaptive immune responses play an important role in controlling influenza virus infection, according to a study, published in the Open Access journal PLoS Computational Biology, by researchers from Oaklan ...
Medical research
Jun 28, 2012 |
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Branching out: A mathematical law of dendritic connectivity
(Medical Xpress) -- That the brain is evolution at its finest is perhaps best demonstrated by the beauty, complexity and diversity of dendrites – tree-like structures that form neural circuits by connecting ...
Neuroscience
Jun 28, 2012 |
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Researchers find that pre-existing mutations can lead to drug resistance in HIV virus
In a critical step that may lead to more effective HIV treatments, Harvard scientists have found that, in a small number of HIV patients, pre-existing mutations in the virus can cause it to develop resistance to the drugs ...
HIV & AIDS
Jun 07, 2012 |
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Google goes cancer: Researchers use search engine algorithm to find cancer biomarkers
The strategy used by Google to decide which pages are relevant for a search query can also be used to determine which proteins in a patient's cancer are relevant for the disease progression. Researchers from Dresden University ...
Cancer
May 17, 2012 |
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Sloppy shipping of human retina leads researchers to discover new treatment path for eye disease
Sloppy shipping of a donated human retina to an Indiana University researcher studying a leading cause of vision loss has inadvertently helped uncover a previously undetected mechanism causing the disease. ...
Ophthalmology
May 04, 2012 |
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New research may have discovered how memories are encoded in our brains
University of Alberta led research may have discovered how memories are encoded in our brains.
Neuroscience
Mar 19, 2012 |
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