Women twice as likely to suffer infection with kidney stones and other urinary blockages

While more men than women develop kidney stones and other obstructions in the urinary tract, women are more than twice as likely to suffer infections related to the condition, according to a new study led by Henry Ford Hospital researchers.

The researchers also found significantly higher rates of complications following one of two urgent treatments for the effects of urolithiasis – or stones in the kidneys and urinary tract – but stressed that this finding is based on preliminary and more research is needed.

The findings were published today in the peer-reviewed European Urology, the official publication of the European Association of Urology.

Not only did the study find that women are far more susceptible to infection when they develop urolithiasis, it also showed that the incidence of infection, including – a potentially fatal inflammation throughout the body touched off by infection –is on the rise.

The rate of related deaths, however, held steady, whom the researchers said is likely a result of "broad improvement in the management of sepsis and the critically ill."

"The research study was conducted because the rate of related to urolithiasis was not known, and evidence was unclear about the best method for treating it," said the study's lead author, Jesse Sammon, DO, Urology Resident at Henry Ford's Vattikuti Urology Institute.

Nearly 400,000 hospitalized with infected urolithiasis from 1999-2009 were identified in the Nationwide Inpatient Sample, the largest all-payer inpatient care database in the U.S. Researchers then determined how often they were treated with either of two techniques – retrograde ureteral catheterization, or RUC, and percutaneous nephrostomy, or PCN.

In RUC, a is inserted through the ureter to drain blocked urine and relieve pressure on the kidney. With PCN, a surgical instrument is used to pierce the patient's back, and then the kidney.

During the 10-year period studied by the researchers, the incidence of infected urolithiasis in increased from 15.5 per 100,000, to 27.6. In men, there was an increase of 7.8 per 100,000, to 12.1. Related sepsis rose from 6.9 percent of urolithiasis patients to 8.5 percent, and severe sepsis increased from 1.7 percent to 3.2 percent.

While higher rates of sepsis, severe sepsis and prolonged hospitals stays were found to be associated to PCN, the researchers cautioned that certain important variables required for comparison are not included in available data.

So conclusions that might be used to guide current and future treatment options would be hypothetical, they said, "demonstrating the pressing need for further study."

Related Stories

Recommended for you

Dengue fever strikes models in Japan

41 minutes ago

A worsening outbreak of dengue fever in Japan has claimed its first celebrities—two young models sent on assignment to the Tokyo park believed to be its source.

Japanese researchers develop 30-minute Ebola test

43 minutes ago

Japanese researchers said Tuesday they had developed a new method to detect the presence of the Ebola virus in 30 minutes, with technology that could allow doctors to quickly diagnose infection.

Senegal monitors contacts of 1st Ebola patient

13 hours ago

Senegalese authorities on Monday were monitoring everyone who was in contact with a student infected with Ebola who crossed into the country, and who has lost three family members to the disease.

Cerebral palsy may be hereditary

18 hours ago

Cerebral palsy is a neurological developmental disorder which follows an injury to the immature brain before, during or after birth. The resulting condition affects the child's ability to move and in some ...

19 new dengue cases in Japan, linked to Tokyo park

Sep 01, 2014

Japan is urging local authorities to be on the lookout for further outbreaks of dengue fever, after confirming another 19 cases that were contracted at a popular local park in downtown Tokyo.

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

ArtflDgr
1 / 5 (1) Sep 26, 2012
but but they are superior equals...