Women twice as likely to suffer infection with kidney stones and other urinary blockages

While more men than women develop kidney stones and other obstructions in the urinary tract, women are more than twice as likely to suffer infections related to the condition, according to a new study led by Henry Ford Hospital researchers.

The researchers also found significantly higher rates of complications following one of two urgent treatments for the effects of urolithiasis – or stones in the kidneys and urinary tract – but stressed that this finding is based on preliminary and more research is needed.

The findings were published today in the peer-reviewed European Urology, the official publication of the European Association of Urology.

Not only did the study find that women are far more susceptible to infection when they develop urolithiasis, it also showed that the incidence of infection, including – a potentially fatal inflammation throughout the body touched off by infection –is on the rise.

The rate of related deaths, however, held steady, whom the researchers said is likely a result of "broad improvement in the management of sepsis and the critically ill."

"The research study was conducted because the rate of related to urolithiasis was not known, and evidence was unclear about the best method for treating it," said the study's lead author, Jesse Sammon, DO, Urology Resident at Henry Ford's Vattikuti Urology Institute.

Nearly 400,000 hospitalized with infected urolithiasis from 1999-2009 were identified in the Nationwide Inpatient Sample, the largest all-payer inpatient care database in the U.S. Researchers then determined how often they were treated with either of two techniques – retrograde ureteral catheterization, or RUC, and percutaneous nephrostomy, or PCN.

In RUC, a is inserted through the ureter to drain blocked urine and relieve pressure on the kidney. With PCN, a surgical instrument is used to pierce the patient's back, and then the kidney.

During the 10-year period studied by the researchers, the incidence of infected urolithiasis in increased from 15.5 per 100,000, to 27.6. In men, there was an increase of 7.8 per 100,000, to 12.1. Related sepsis rose from 6.9 percent of urolithiasis patients to 8.5 percent, and severe sepsis increased from 1.7 percent to 3.2 percent.

While higher rates of sepsis, severe sepsis and prolonged hospitals stays were found to be associated to PCN, the researchers cautioned that certain important variables required for comparison are not included in available data.

So conclusions that might be used to guide current and future treatment options would be hypothetical, they said, "demonstrating the pressing need for further study."

Related Stories

Recommended for you

The struggle between humans and parasites

date 1 hour ago

The battle between humanity and parasites is a constant struggle. As parasites grow stronger by developing immunities, new treatments must be created in response. On the frontlines of this struggle are parasitologists, scientists ...

Chikungunya kills 25 in Colombia

date 4 hours ago

The virus chikungunya has killed 25 people in Colombia in less than a year, the National Health Institute said Monday.

Time to move Lyme Disease Awareness Month to April?

date 15 hours ago

The month of May brings many things, among them Mother's Day, tulips, and Lyme Disease Awareness campaigns. But according to Dr. Richard S. Ostfeld, a disease ecologist at the Cary Institute of Ecosystem ...

An explanation of wild birds' role in avian flu outbreak

date 17 hours ago

Wild birds are believed to be behind the first major widespread outbreak of bird flu in the United States. The H5N2 virus has cost Midwestern turkey and chicken producers almost 13 million birds since early March, including ...

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

ArtflDgr
Sep 26, 2012
but but they are superior equals...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.