The present variants of cancer immunotherapy such as immune checkpoint blockades only benefit a small subset of patients due to its immunosuppressive tumor microenvironment. The capacity to vaccinate tumors and reduce immunosuppression ...
New insights into a population of tumor-infiltrating T cells may ultimately allow doctors to predict how patients will respond to checkpoint blockade immunotherapy, a form of cancer treatment with advantages that doctors ...
Researchers at the Washington University School of Medicine, St. Louis, have discovered a potential new target for cancer immunotherapy in transposable elements (TEs), short segments of DNA that can move around the genome.
A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg-Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new ...
Mar 1, 2021
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A second biological pathway that signals immune cells not to engulf and kill cancer cells has been identified by researchers at the Stanford University School of Medicine.
Nov 27, 2017
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Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of ...
Apr 2, 2015
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Tumor cells are "cunning," according to Peter Yingxiao Wang. They have a nefarious way of evading the human immune responses that fight back against these cancerous invaders. Tumor cells express programmed death-ligand 1 ...
May 2, 2024
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Cancer cells grow and spread by hiding from the body's immune system. Immunotherapy allows the immune system to find and attack hidden cancer cells, helping cancer patients live longer lives. However, many patients get little ...
Apr 16, 2024
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Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests ...
Mar 19, 2024
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The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma.
Mar 1, 2024
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