Diseases, Conditions, Syndromes

Assessing the mechanisms for liver fibrosis

Chronic liver injury results in the development of liver fibrosis in approximately 25% of individuals in response to diverse insults, and several aspects of the development of liver injury appear to be common to a variety ...

Diabetes

Unraveling the link between obesity, diabetes and endotrophin

With obesity rates projected to continue rising globally, there is an urgent need to understand the intricate mechanisms that contribute to metabolic diseases such as diabetes. Addressing this critical issue head-on, Jiyoung ...

Ophthalmology

Understanding the metabolites underlying eye development

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

Oncology & Cancer

Researchers unravel metabolic regulation in aneuploid tumor cells

A research team led by Prof. Yang Zhenye from the University of Science and Technology of China (USTC) of Chinese Academy of Sciences (CAS), in collaboration with Guo Jing from the First Affiliated Hospital of USTC, has made ...

Medical research

A step toward treating chemotherapy-resistant prostate cancer

Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications—cisplatin. Now, researchers reporting in ACS Central Science have developed the first ...

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