News tagged with cellular dna
In cancer, an embryonic gene-silencing mechanism gone awry
There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our ...
Genetics
Oct 04, 2012 |
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Researchers find cause of chemotherapy resistance in melanoma
Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.
Cancer
Sep 17, 2012 |
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Study illuminates roles of novel epigenetic chemical in the brain
Researchers from the Centre for Addiction and Mental Health (CAMH) have identified a new role of a chemical involved in controlling the genes underlying memory and learning.
Genetics
Sep 17, 2012 |
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Cell death mystery yields new suspect for cancer drug development
A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.
Cancer
Sep 13, 2012 |
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Gene therapy restores sense of smell, may aid research into other diseases caused by cilia defects
Scientists have restored the sense of smell in mice through gene therapy for the first time—a hopeful sign for people who can't smell anything from birth or lose it due to disease.
Medical research
Sep 02, 2012 |
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Gene 'switch' may explain DiGeorge syndrome severity
The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.
Genetics
Aug 23, 2012 |
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Detector of DNA damage: Structure of a repair factor revealed
Double-stranded breaks in cellular DNA can trigger tumorigenesis. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich, Germany, have determined the structure of a protein involved in the repair and signaling ...
Medical research
Jun 19, 2012 |
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The neurological basis for fear and memory
Fear conditioning using sound and taste aversion, as applied to mice, have revealed interesting information on the basis of memory allocation.
Neuroscience
Jun 18, 2012 |
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Scientists reprogram cancer cells with low doses of epigenetic drugs
Experimenting with cells in culture, researchers at the Johns Hopkins Kimmel Cancer Center have breathed possible new life into two drugs once considered too toxic for human cancer treatment. The drugs, azacitidine (AZA) ...
Cancer
Mar 22, 2012 |
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How mitochondrial DNA defects cause inherited deafness
(Medical Xpress) -- Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed ...
Medical research
Feb 17, 2012 |
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Three is the magic number: A chain reaction required to prevent tumor formation
Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in re-establishing the presence ...
Cancer
Jan 20, 2012 |
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Orphaned children exhibit genetic changes that require nurturing parents
Children who experience the stress of separation at birth from biological parents and are brought up in orphanages undergo biological consequences such as changes in their genome functioning, Yale School of ...
Psychology & Psychiatry
Dec 05, 2011 |
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A brighter future for infertility treatment: study
(Medical Xpress) -- Male infertility could soon have a boost through new treatments at a sub-DNA 'epigenetic' level, according to researchers from The Australian National University.
Genetics
Dec 05, 2011 |
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Medical researchers decoding the aging process
Scientists are beginning to decode the complex biology of aging and are optimistic that recent advances in research may lead to treatments that can slow or even reverse degeneration and disease.
Medical research
Nov 15, 2011 |
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How major signaling pathways are wired to our genome gives new insight into disease processes
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Medical research
Oct 27, 2011 |
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