Brain-building gene plays key role in gut repair
(Medical Xpress)—A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be ...
Genetics
Apr 05, 2013 |
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Study demonstrates effects of mutant IDH1 and IDH2 inhibitors in primary tumor models
Agios Pharmaceuticals announced today the publication of two articles in the journal Science by Agios scientists and their collaborators demonstrating the effects of the company's small molecule isocitrate dehydrogenase 1 and ...
Cancer
Apr 04, 2013 |
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Just 'weight' until menopause: How estrogen deficiency affects women's fat absorption
Women tend to carry excess fat in their hips and thighs, while men tend to carry it on their stomachs. But after menopause, things start to change: many women's fat storage patterns start to resemble those of men. This indicates ...
Diabetes
Mar 27, 2013 |
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Immortality gene mutation identifies brain tumors, other cancers
Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...
Cancer
Mar 18, 2013 |
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Combating the deathly Coronavirus
Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate ...
Diseases, Conditions, Syndromes
Mar 15, 2013 |
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Cord blood effective alternative to matched donor stem cells for kids with rare disorder
Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's ...
Medical research
Mar 14, 2013 |
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3 Questions: MIT biologist on new resveratrol study
In the early 1990s, MIT professor Leonard Guarente discovered that sirtuins, a class of proteins found in nearly all animals, protect against the effects of aging in yeast; similar effects have since been ...
Medical research
Mar 07, 2013 |
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Fanning the flames of tumor growth: Enzyme responsible for protecting chromosome ends stimulates tumorigenesis
Chromosomes are capped by long, repetitive DNA sequences called telomeres. These caps prevent genomic damage by insulating against the steady shortening of DNA ends that naturally accompanies replication. ...
Cancer
Feb 27, 2013 |
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Preventing suicide: A critical next step
Doctors may in the future be able to take a blood test to determine if a patient is suicidal, hopefully decreasing the number of people taking their own lives.
Psychology & Psychiatry
Feb 20, 2013 |
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The same genetic defect causes Pompe disease in both humans and dogs
Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans. Based ...
Genetics
Feb 15, 2013 |
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Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation
Cancer
Feb 12, 2013 |
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A pill so people with celiac disease can eat freely?
(HealthDay)—For people with celiac disease, everyday foods such as bread, pizza crust and muffins are potential enemies. But scientists anticipate that some day a simple pill could help prevent the digestive ...
Diseases, Conditions, Syndromes
Feb 08, 2013 |
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A step towards better understanding of pancreatic cancer
(Medical Xpress)—An international team of scientists has observed that the well-studied protein Sirtuin-1, known for helping cells live longer, also appears to play an important role in pancreatic cancer.
Cancer
Feb 05, 2013 |
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Experimental molecular therapy crosses blood-brain barrier to treat neurological disease
Researchers have overcome a major challenge to treating brain diseases by engineering an experimental molecular therapy that crosses the blood-brain barrier to reverse neurological lysosomal storage disease in mice.
Medical research
Feb 04, 2013 |
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Ravicti approved for urea cycle disorders
(HealthDay)—Ravicti (glycerol phenylbutyrate) has been approved by the U.S. Food and Drug Administration to treat certain urea cycle disorders (UCDs) in people 2 years and older.
Medications
Feb 01, 2013 |
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