Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting pathogenesis features neuroinflammation, ...
Feb 12, 2024
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New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.
Jul 31, 2023
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A simple vitamin could successfully treat a rare but potentially fatal genetic disease, according to research led by a Concordia undergraduate student.
Mar 7, 2023
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Nearly 100% of cases of amyotrophic lateral sclerosis—the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease—involve the buildup of a protein called TDP-43.
Feb 27, 2023
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Researchers working with UMass Chan Medical School's Translational Institute for Molecular Therapeutics announced progress in developing a vector to deliver gene replacement therapy in mice models with Cockayne syndrome, ...
Jan 30, 2023
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ALS is a fatal neurodegenerative disease causing a rapid loss of motor function, which usually results in a serious condition with early death within a few years. So far, early and precise diagnosis of the disease has been ...
Dec 9, 2020
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A mechanism for amyotrophic lateral sclerosis (ALS) development has been discovered at Umeå University, Sweden. The researchers report that proteins with a defect structure spread the deformation to other proteins. The discovery ...
Sep 4, 2018
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Scientists at the UNC School of Medicine have made a significant advance in the understanding of the complex and fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
Apr 16, 2018
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Researchers at Western University have uncovered a unique neurobiological pathway triggered by head trauma which underlies both Chronic Traumatic Encephalopathy (CTE) and Lou Gehrig's disease.
Jan 16, 2018
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Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular ...
Jul 17, 2017
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