Oncology & Cancer
Genetic switch shuts down lung cancer tumors in mice
Yale researchers manipulated a tiny genetic switch and halted growth of aggressive lung cancer tumors in mice and even prevented tumors from forming.
Oct 25, 2012
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Page 2 - News tagged with genetic switches
Immunology
Proteins team up to turn on T cells
The fates of various cells in our bodies—whether they become skin or another type of tissue, for example—are controlled by genetic switches. In a new study, Caltech scientists investigate the switch for T cells, which ...
Jul 15, 2016
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Oncology & Cancer
Synthetic biology approaches to improving immunotherapy
The AACR 2018 Meeting in Chicago is ending today and has featured the major new results in cancer treatment and immunotherapy treatments in particular. Immunotherapy, the use of the patient's own immune system to attack their ...
Apr 20, 2018
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Neuroscience
Flip of a single molecular switch makes an old brain young
The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have ...
Mar 6, 2013
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Oncology & Cancer
Physicists decode decision circuit of cancer metastasis
Cancer researchers from Rice University have deciphered the operating principles of a genetic switch that cancer cells use to decide when to metastasize and invade other parts of the body. The study found that the on-off ...
Oct 24, 2013
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Genetics
Reactivating silenced fetal hemoglobin genes could counter sickle cell–related diseases
Researchers from multiple institutions in China have found a way to use gene editing to reactivate dormant fetal oxygen-transporting proteins in adult blood cells to potentially reverse a wide range of blood disorders.
Genetics
Scientists find way to predict and control gene expression
(Medical Xpress)—EPFL scientists have developed a "guide" that can be used to precisely predict the number of proteins a given gene will produce under varying conditions. This work will help biologists to engineer cells.
Aug 19, 2013
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Oncology & Cancer
A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Switching off the enzyme that adds protective caps to chromosome ends could help fight many types of cancer, A*STAR researchers have shown. The team demonstrated the treatment's potential by using it to thwart tumor growth ...
Dec 20, 2018
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Medical research
Evolutionary conservation of fat metabolism pathways
By virtue of having survived, all animals-from flies to man-share a common expertise. All can distinguish times of plenty from famine and adjust their metabolism or behavior accordingly. Failure to do so signals either extinction ...
May 12, 2011
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Genetics
Researchers develop editing toolkit for customizing zebrafish genomes
Mayo Clinic researchers and an international team of scientists have developed a highly-efficient means of editing zebrafish genomes for research purposes, eliminating a bottleneck that has stymied biomedical scientists from ...
Sep 23, 2012
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