Diseases, Conditions, Syndromes

Genotyping study shows how COVID variants can be detected more rapidly

Genotyping technology detects COVID variants more quickly and cheaply than ever before—according to research from the University of East Anglia and the UK Health Security Agency. The new study published in The Lancet Microbe ...

Genetics

New informatics software helps identify rare genetic variants

A team of researchers at Indiana University School of Medicine has developed specialized bioinformatics software designed to identify rare genetic variants in whole-genome sequencing studies. Zilin Li, Ph.D., assistant professor ...

Genetics

Romantic relationship dynamics may be in our genes

Variations in a gene called CD38, which is involved in attachment behavior in non-human animals, may be associated with human romantic relationship dynamics in daily life, according to a study published in Scientific Reports.

Genetics

Happy in marriage? Genetics may play a role

People fall in love for many reasons—similar interests, physical attraction, and shared values among them. But if they marry and stay together, their long-term happiness may depend on their individual genes or those of ...

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Genotype

The genotype is the genetic constitution of a cell, an organism, or an individual (i.e. the specific allele makeup of the individual) usually with reference to a specific character under consideration. For instance, the human albino gene has two allele forms, dominant A and recessive a, and there are three possible genotypes- AA (homozygous dominant), Aa (heterozygous), and aa (homozygous recessive).

It is a generally accepted theory that inherited genotype, transmitted epigenetic factors, and non-hereditary environmental variation contribute to the phenotype of an individual.

Non-hereditary DNA mutations are not classically understood as representing the individual's genotype. Hence, scientists and physicians sometimes talk for example about the (geno)type of a particular cancer, that is the genotype of the disease as distinct from the diseased.

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