HIV & AIDS

Is it possible to deliver a knockout punch to HIV?

With a global focus on strategies to curb expansion of a fast-moving coronavirus pandemic, the question again has arisen: What more is being done about HIV, a scourge that has lasted more than 40 years—is a cure finally ...

HIV & AIDS

Nanoparticles loaded with bee venom kill HIV

(Medical Xpress)—Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers at Washington University School of Medicine in St. ...

Genetics

Glowing cats help in fight against AIDS, other diseases

Mayo Clinic researchers have developed a genome-based immunization strategy to fight feline AIDS and illuminate ways to combat human HIV/AIDS and other diseases. The goal is to create cats with intrinsic immunity to the feline ...

Medications

How a novel drug pushes the HIV capsid to breaking point

Just over a year ago, the European Union and the US Food and Drug Administration approved a new anti-retroviral drug to treat human immunodeficiency virus (HIV) infections. Lenacapavir is the first drug available to patients ...

HIV & AIDS

Researchers pinpoint most likely source of HIV rebound infection

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify ...

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Feline immunodeficiency virus

Feline immunodeficiency virus (FIV) is a lentivirus that affects domesticated housecats worldwide and is the causative agent of feline AIDS. Approximately 11% of cats worldwide, and about 2.5% of cats in the USA, are infected with FIV. FIV differs taxonomically from two other feline retroviruses, feline leukemia virus (FeLV) and feline foamy virus (FFV) and is more closely related to human immunodeficiency virus HIV. Within FIV, five subtypes have been identified based on amino acid sequence differences coding for the viral envelope. FIV is the only non-primate lentivirus to cause an AIDS-like syndrome, but FIV is not always a death sentence for cats, as they can live relatively healthily as carriers and transmitters of the disease for many years. A vaccine is available although its efficacy remains uncertain, and cats will test positive for FIV antibodies after vaccination.

FIV was first discovered in 1986 in a colony of cats that had a high prevalence of opportunistic infections and degenerative conditions, and has since been identified as an endemic disease in domestic cat populations worldwide .

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