Researchers have developed a genome editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people.
Sep 24, 2018
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Mitochondrial genetic engineering is the adaptation of genetic engineering techniques to specific mitochondrial problems. Although it is not common to be born with severe mitochondrial issues, we will all eventually have ...
New research from USC has uncovered a previously unknown genetic risk factor for Alzheimer's disease and related dementias. The study provides insights on how these conditions, and other diseases of aging, might one day be ...
Sep 21, 2018
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Wrinkled skin and hair loss are hallmarks of aging. What if they could be reversed?
Jul 20, 2018
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Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have provided valuable information about the defense mechanisms of the immune system during the early stages of the response to pathogens ...
Jul 10, 2018
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Genome analysis today is basically blind. It typically proceeds by randomly inspecting a smattering of possible variants that are only loosely associated with some disease or physical trait. Unless you already have a major ...
Mothers with mitochondrial DNA mutations often give birth to children who face incurable and fatal illnesses. But a much-studied form of mitochondrial replacement (MR) could prevent the transmission of such diseases from ...
Mar 28, 2018
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Mitochondria are cellular organelles with their own DNA. Their role in power generation makes them susceptible to oxidative damage, including the formation of DNA-damaging chemical complexes called adducts.
Feb 23, 2018
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As part of a breast-cancer diagnosis, doctors analyze the tumor to determine which therapies might best attack the malignancy. But for patients whose cancer is triple-negative—that is, lacking receptors for estrogen, progesterone ...
Feb 3, 2018
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Researchers have shown for the first time how children can inherit a severe - potentially fatal - mitochondrial disease from a healthy mother. The study, led by researchers from the MRC Mitochondrial Biology Unit at the University ...
Jan 15, 2018
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