Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that ...
May 3, 2024
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A new meta-analysis published in OMICS: A Journal of Integrative Biology helps shed light on how changes in mitochondria-related gene expression may cause the cardiotoxicity associated with the cancer therapy trastuzumab.
Mar 18, 2024
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In a first, Tel Aviv University researchers have discovered that the production and regulation of mitochondrial organelles in the brain's nerve cells (neurons) becomes significantly impaired with the deletion of a gene called ...
Jan 10, 2024
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Modulating the activity of a kinase in motor neurons may help mitigate mitochondrial defects and other symptoms of spinal muscular atrophy, offering a new therapeutic avenue for the devastating disease, according to a Northwestern ...
Dec 5, 2023
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Northwestern Medicine scientists have revealed how a gene considered essential for histone modification regulates skin development, according to a recent study published in Nature Communications.
Sep 6, 2023
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Researchers at the University of California at Los Angeles have analyzed RNA editing in postmortem brains of four schizophrenia cohorts and uncovered a significant and reproducible trend of hypo-editing in patients of European ...
The newest vitamin B3 family member, nicotinamide riboside (NR) has been found to have beneficial effects on mitochondria in the human muscle. Currently, mitochondrial dysfunction cannot be treated. Recent findings from the ...
Feb 9, 2023
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Researchers at the University of Pittsburgh School of Medicine, U.S. present the first evidence of 12-hour cycles of gene activity in the human brain. Published in the open access journal PLOS Biology on January 24, the study ...
Jan 24, 2023
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Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant ...
Jan 24, 2023
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A new research paper was published on the cover of Aging entitled "Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence."
Dec 16, 2022
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