Neuroscience

Neural crest cell migration in Hirschsprung disease

Ankush Gosain, MD, Ph.D., of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous ...

Medical research

Scientists tissue engineer human intestines and functioning nerves

Scientists report in Nature Medicine using human pluripotent stem cells to grow human intestinal tissues that have functioning nerves in a laboratory, and then using these to recreate and study a severe intestinal nerve disorder ...

Cardiology

Mending broken hearts with neural crest cells

Zebrafish—striped fish a few centimeters long—have the ability to regrow up to 20 percent of their hearts after sustaining major damage. Now, Caltech scientists have discovered that embryonic cells from the hindbrain, ...

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