A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study ...
Nov 9, 2023
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Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. ...
Jul 5, 2023
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Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate ...
Feb 20, 2023
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Scientists at the University of Augsburg and Helmholtz Munich have made an important breakthrough in better understanding early processes in the development of type 2 diabetes by identifying a previously unknown transmission ...
Feb 13, 2023
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Insulin is a vital hormone produced by pancreatic beta cells. Type 1 diabetes is caused by the destruction of these cells, which results in patients having to replace the lost insulin with multiple daily injections.
Mar 3, 2022
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With nearly 10% of the world's population affected, type 2 diabetes is a major public health issue. An excessively sedentary lifestyle and excessively caloric diet encourage the development of this metabolic disease by altering ...
Jan 12, 2022
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Researchers have discovered a previously unknown way that pancreatic cells decide how much insulin to secrete. It could provide a promising new target to develop drugs for boosting insulin production in people with Type 2 ...
Nov 13, 2020
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Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at Vanderbilt ...
Feb 21, 2020
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A new study helps to explain the mechanism by which pancreatic cells secrete high levels of insulin during the early stages of diabetes.
Dec 20, 2019
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Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.
Nov 7, 2017
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