Increased stability of a misfolded protein linked to age of onset of common form of motor neuron disease
Neurodegenerative diseases are characterized by the aggregation of misfolded proteins, which accumulate to form insoluble clumps within or around nerve cells. In the adult motor neuron disease amyotrophic ...
Medical research
Apr 22, 2013 |
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Study reveals Rx target for HPV, Hep C and related cancers
New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" ...
Medical research
Apr 10, 2013 |
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Parkinson's disease protein gums up garbage disposal system in cells
(Medical Xpress)—Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.
Parkinson's & Movement disorders
Mar 28, 2013 |
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New compound holds high promise in battling kidney cancer
Chemists at the University of California, Riverside have developed a compound that holds much promise in the laboratory in fighting renal (kidney) cancer.
Cancer
Feb 19, 2013 |
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Scientists find protein that reins in runaway network
Marked for death with molecular tags that act like a homing signal for a cell's protein-destroying machinery, a pivotal enzyme is rescued by another molecule that sweeps the telltale targets off in the nick of time.
Medical research
Jan 22, 2013 |
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Poison for cancer cells: New method identifies active agents in mixtures of hundreds of substances
In their quest for new agents, pharmaceutical researchers test millions of substances all over the world. They like using color-forming reactions to identify new molecules. However, in intensively colored ...
Cancer
Dec 20, 2012 |
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Researchers shed light on new multiple myeloma therapy
Researchers from John Theurer Cancer Center at HackensackUMC, one of the nation's 50 best hospitals for cancer, played leading roles in three separate multi-center studies with the new proteasome inhibitor carfilzomib published ...
Cancer
Jul 25, 2012 |
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Substance interfering with the cells handling of protein waste could become new cancer drug
(Medical Xpress) -- Researchers at Karolinska Institutet have identified a new kind of cancer drug that has been shown to be effective against tumours in different experimental systems. An article published in Nature Medicine shows ...
Cancer
Nov 07, 2011 |
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Analysis of sperm differentiation reveals new mode of proteasome regulation
(Medical Xpress) -- Early in development, cells undergo a controlled demolition that helps to shape their raw, pliable material into the specialized forms they must have to do their jobs as adults. The process ...
Medical research
May 02, 2011 |
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