Oncology & Cancer

New approach attacks 'undruggable' cancers from the outside in

Cancer researchers have made great strides in developing targeted therapies that treat the specific genetic mutations underlying a patient's cancer. However, many of the most common cancer-causing genes are so central to ...

Neuroscience

Star-shaped brain cells orchestrate neural connections

Brains are made of more than a tangled net of neurons. Star-like cells called astrocytes diligently fill in the gaps between neural nets, each wrapping itself around thousands of neuronal connections called synapses. This ...

Diseases, Conditions, Syndromes

World-first trial for universal flu vaccine

The world's first widespread human testing of a flu vaccine which researchers hope will protect more over 65-year-olds against influenza has begun in the NHS.

Immunology

Clustering for health

When functioning appropriately, the immune system protects against multiple threats such as pathogens, disease-causing microbes, and tumors. However, when the immune system is inappropriately activated, it attacks the body, ...

Medical research

Researchers gain insights to redirect leading HIV cure strategy

Research at the University of Illinois at Urbana-Champaign has provided the first evidence that viruses and hosts share highly similar regulatory sequences in their promoters—the initiation sequences of human genes that ...

Oncology & Cancer

Savior of T-cells may be enemy of liver immune cells

Researchers at Houston Methodist demonstrated that a surface protein called OX40, responsible for keeping one type of immune system cell alive, can trigger the death of liver immune cells, in turn starting a chain reaction ...

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