News tagged with therapeutic target

Related topics: cancer cells , protein , mouse model , cancer , breast cancer




Study identifies new approach to improving treatment for MS and other conditions

(Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved ...

Alzheimer's disease & dementia created May 17, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists find potential therapeutic target for Cushing's disease

Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this ...

Diseases, Conditions, Syndromes created May 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Type 1 diabetes and heart disease linked by inflammatory protein

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...

Inflammatory disorders created May 07, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Study uses Botox to find new wrinkle in brain communication

National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel ...

Medical research created May 02, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New agent might control breast-cancer growth and spread

A new study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) suggests that an unusual ...

Cancer created Apr 22, 2013 | popularity not rated yet | comments 0 | with audio podcast

Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.

Cancer created Apr 19, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers discover new treatment possibilities for Lou Gehrig's disease

(Medical Xpress)—A team led by Dr. Alex Parker, a professor of pathology and cellular biology and a researcher at the University of Montreal Hospital Research Centre (CRCHUM), has identified an important ...

Neuroscience created Apr 17, 2013 | popularity 2.5 / 5 (2) | comments 0 | with audio podcast

Genetic variation contributes to pulmonary fibrosis risk

A newly published study of patients with pulmonary fibrosis has discovered multiple genetic variations that should help with future efforts to treat the disease.

Genetics created Apr 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer

Platinum compounds, such as cisplatin and carboplatin, induce DNA cross-linking, prohibiting DNA synthesis and repair in rapidly dividing cells. They are first line therapeutics in the treatment of many solid tumors, but ...

Cancer created Apr 15, 2013 | popularity not rated yet | comments 0

Peptides for the treatment of severe diseases

A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively ...

Medical research created Apr 15, 2013 | popularity 5 / 5 (1) | comments 0

New genetic screen paves the way for long-sought treatments for liver disease

Chronic liver failure is a major health problem that causes about one million deaths around the world each year. A study published April 11th by Cell Press in the journal Cell reveals a new type of screen for identifying genes ...

Medical research created Apr 11, 2013 | popularity not rated yet | comments 0

Fractalkine: New protein target for controlling diabetes

Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release ...

Diabetes created Apr 11, 2013 | popularity not rated yet | comments 0 | with audio podcast

U-M researchers find new way to clear cholesterol from the blood

Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.

Cardiology created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers identify transcription factors that regulate retinal vascularization

The retina is a highly vascularized tissue, but too much or too little vascularization can lead to visual impairment and diseases such as familial exudative vitreoretinopathy or macular degeneration. In this issue of the ...

Medical research created Apr 08, 2013 | popularity not rated yet | comments 0

Researchers say one specific microrna promotes tumor growth and cancer spread

Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in ...

Cancer created Apr 03, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast