News tagged with transcription factors
Related topics: genes , cells , gene expression , stem cells , dna sequences
New target discovered for food allergy treatment
Researchers at National Jewish Health have discovered a novel target for the treatment of food allergies. Erwin Gelfand, MD, and his colleagues report in the October 2012 issue of the Journal of Allergy and Clinical Immunology that l ...
Immunology
Nov 01, 2012 |
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Stay-at-home transcription factor prevents neurodegeneration
A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...
Medical research
Oct 29, 2012 |
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Lactation protein suppresses tumors and metastasis in breast cancer, scientists discover
A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton ...
Cancer
Oct 24, 2012 |
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Transcription factor Prox1 controls hippocampal cellular diversity, researchers find
As is true of many brain structures, the hippocampus, which plays a central role in memory and learning, is made up of multiple cell types organized into domains controlling different functions. Distinct ...
Neuroscience
Oct 16, 2012 |
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Of mice and men
The use of carefully chosen animal models often underlies crucial medical advances. A perfect example is provided by the recent demonstration that a known drug, imatinib, can be used to treat a rare but ...
Cancer
Oct 15, 2012 |
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Notch control of cell architecture: Potential implications for future cancer therapy
Dissecting the mechanisms implicated in cell architecture should provide new insights for understanding development and tissue morphogenesis in general. An European study focused on the role of the Notch ...
Cancer
Oct 05, 2012 |
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Study finds new molecular pathways involved with autoimmune diseases, potential implications for therapies
Teamwork between a pair of transcription factors may be responsible for regulating the functioning of Th17 cells, which when found in excessive amounts are believed to play a major role in many autoimmune ...
Immunology
Sep 28, 2012 |
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Researchers find possible key to regulation of ovarian cancer stem cells
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered that the micro ribonucleic acid miR-214 plays a critical role in regulating ovarian cancer stem cell properties. This knowledge, said the researchers, ...
Cancer
Sep 27, 2012 |
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Mouse pancreatic stem cells successfully differentiate into insulin producing cells
In a study to investigate how transplanted islet cells can differentiate and mature into insulin-producing pancreatic cells, a team of Japanese researchers found that using a specific set of transcription factors (proteins ...
Medical research
Sep 25, 2012 |
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Self-regulating networks dictate the genetic program of tumor cells
Scientists at Charité – Universitätsmedizin Berlin could explain a yet unknown regulatory network that controls the growth of tumor cells. Understanding such networks is an important task in molecular tumor biology in ...
Cancer
Sep 25, 2012 |
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Stem cell therapy for spinal cord injury
Stem cells are considered promising agents for the recovery of spinal cord injuries. European scientists explore their abilities and plan future therapeutic strategies.
Medical research
Sep 25, 2012 |
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Study explains decrease in insulin-producing beta cells in diabetes
Scientists generally think that reduced insulin production by the pancreas, a hallmark of type 2 diabetes, is due to the death of the organ's beta cells. However, a new study by Columbia University Medical ...
Diabetes
Sep 13, 2012 |
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Research finds key molecules involved in forming long-term memories
How does one's experience of an event get translated into a memory that can be accessed months, even years later? A team led by University of Pennsylvania scientists has come closer to answering that question, identifying ...
Medical research
Sep 10, 2012 |
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HIF gene mutation found in tumor cells offers new clues about cancer metabolism
For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified in cancer tumor cells.
Cancer
Sep 06, 2012 |
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ENCODE project: Yale team finds order amidst the chaos within the human genome
The massive Encyclopedia of DNA Elements (ENCODE) unveiled Sept. 5 reveals a human genome vastly more rich and complex than envisioned even a decade ago. In a key supporting paper published in the journal Nature, the lab of ...
Genetics
Sep 05, 2012 |
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