News tagged with tumor biology
New drug shows promise in ability to fight rare type of breast cancer
Researchers in the University of Delaware's Department of Biological Sciences are investigating a new drug that has shown positive results in early tests of its ability to fight a rare and aggressive form ...
Cancer
Mar 08, 2013 |
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Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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Researchers find cancer aggression differences in different types of prostate cells
(Medical Xpress)—A research team made up of representatives from several cancer research centers in the United States has found that cancers that develop in the prostate of mice may be either aggressive or sluggish depending ...
Cancer
Feb 25, 2013 |
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Combo of Avastin, second drug shows promise fighting brain cancer, study finds
The drug bevacizumab, also known by the trade name Avastin, shrinks tumors briefly in patients with an aggressive brain cancer known as glioblastoma multiforme, but then they often grow again and spread throughout the brain ...
Cancer
Feb 14, 2013 |
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Researchers discover biological diversity in triple-negative breast cancer
Triple-negative breast cancers are more biologically diverse than previously believed and classification should be expanded to reflect this heterogeneity, according to University of North Carolina researchers.
Cancer
Feb 13, 2013 |
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Protein that represses critical checkpoint protein for cellular growth helps drive tumor development
(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth ...
Cancer
Feb 13, 2013 |
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Reassuring evidence: Anticancer drug does not accelerate tumor growth after treatment ends
Studies in animals have raised concerns that tumors may grow faster after the anticancer drug sunitinib is discontinued. But oncologists and physicists who collaborated to analyze data from the largest study ...
Cancer
Feb 07, 2013 |
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RNA promotes metastasis in lung cancer
The vast majority – approximately 80 percent – of our DNA does not code for proteins, yet it gets transcribed into RNA. These RNA molecules are called non-coding and fulfill multiple tasks in the cell. Alongside a well-studied ...
Cancer
Feb 05, 2013 |
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Researchers use new molecular inhibitors to successfully hit difficult cancer target
Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.
Cancer
Feb 05, 2013 |
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Epigenetic marker 5hmC opens door to studying its role in developmental disorders and disease
Nearly every cell in the human body carries a copy of the full human genome. So how is it that the cells that detect light in the human eye are so different from those of, say, the beating heart or the spleen?
Genetics
Feb 04, 2013 |
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Blood vessel cells coax colorectal cancer cells into more dangerous state
Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and ...
Cancer
Feb 01, 2013 |
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Bioelectric signals can be used to detect early cancer
Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...
Medical research
Feb 01, 2013 |
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Common genetic alteration found in head and neck cancers may not be key to effective treatment
Although a large majority of head and neck cancers have a deregulation of the PI3K/AKT/mTOR pathway, data recently published in Cancer Research, a journal of the American Association for Cancer Research, indicated that d ...
Cancer
Jan 29, 2013 |
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Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis
Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...
Cancer
Jan 29, 2013 |
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Diabetes drug could hold promise for lung cancer patients
Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...
Cancer
Jan 29, 2013 |
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