Archive: 08/03/2018

Scientists discover a key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, ...

Mar 8, 2018

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Exposure to childhood violence linked to psychiatric disorders

Investing in diminishing socioeconomic status inequalities and in preventing violent events during childhood may improve the mental health of youths from low socioeconomic status backgrounds, according to a study conducted ...

Mar 8, 2018

New options for targeting gene mutation in FA described in nucleic acid therapeutics

Researchers have shown that a wide variety of synthetic antisense oligonucleotides with different chemical modifications can activate the frataxin gene, which contains a mutation that decreases its expression in the inherited ...

Mar 8, 2018

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Researchers find protein that marks difference between cancer and non-cancer cells

A discovery sheds light on how cancerous cells differ from healthy ones, and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers in the future.

Mar 8, 2018

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Scientists assess transmission risk of familial human prion diseases to mice

Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations. To determine whether three of the unstudied mutations are transmissible, scientists from the National Institute ...

Mar 8, 2018

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Research reveals a mechanism that drives ataxia type 1

When the protein ATAXIN1 accumulates in neurons it causes a neurodegenerative condition called spinocerebellar ataxia type 1 (SCA1), a rare disease characterized by progressive problems with balance and breathing difficulties. ...

Mar 8, 2018

Clinical trial matching project sees higher enrollment in breast cancer trials through use of artificial intelligence

Mayo Clinic and IBM Watson Health today unveiled results from early use of the Watson for Clinical Trial Matching, an IBM cognitive computing system. Use of this system in the Mayo Clinic oncology practice has been associated ...

Mar 8, 2018

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Cancer 'signature' first step toward blood test for patients

A discovery by Melbourne researchers could help to identify patients with a particularly aggressive type of lung cancer that are likely to respond to immunotherapies currently used in the clinic to treat other cancers.

Mar 8, 2018

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Scientists zero in on treatment for Charcot-Marie-Tooth disease

About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who can lose their ability to walk and use their hands for fine motor skills. There ...

Mar 8, 2018

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Researchers discover new Rx for allergic contact dermatitis

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has found a promising new treatment for allergic contact dermatitis ...

Mar 8, 2018

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