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Arthritis & Rheumatism

Study offers potential for early diagnosis and therapeutic intervention for rheumatoid arthritis

Currently, there are no cures for rheumatoid arthritis (RA), which affects 40,000 people in Ireland. The disease costs an estimated $22,000 per patient, per year with an overall cost to the health system of ~$608 million. ...

Arthritis & Rheumatism

AI chatbots rival doctors in accuracy for back pain advice, study finds

A new study reveals that artificial intelligence chatbots, such as ChatGPT, may be almost as effective as consulting a doctor for advice on low back pain.

Arthritis & Rheumatism

Study shows AFL players' hip issues begin in early career

Researchers from La Trobe University studied 58 pain-free male Australian Football League (AFL) draftees, finding that nearly half showed hip joint changes on Magnetic Resonance Imaging (MRI) and 20% had a particular hip ...

Arthritis & Rheumatism

Study uncovers key factors in myositis-induced muscle weakness

A study has shed new light on the mechanisms behind idiopathic inflammatory myopathies (myositis), a group of systemic autoimmune disorders known for causing severe muscle weakness, fatigue, and increased mortality.

Arthritis & Rheumatism

Machine learning helps identify rheumatoid arthritis subtypes

A machine-learning tool created by Weill Cornell Medicine and Hospital for Special Surgery (HSS) investigators can help distinguish subtypes of rheumatoid arthritis (RA), which may help scientists find ways to improve care ...

Arthritis & Rheumatism

Surprising mechanism of lupus kidney damage identified

A Berlin-led research team has uncovered critical regulators of severe kidney damage in patients with lupus, an autoimmune disorder affecting an estimated five million people worldwide, most of whom are young women. A small, ...

Arthritis & Rheumatism

Discordance for radiologic, goniometric measures in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), there is discordance between radiological and goniometric measurements of ulnar deviation (UD) at the metacarpophalangeal joints, according to a study published online ...

Arthritis & Rheumatism

New bone chewing role for B cells in rheumatoid arthritis

University of Rochester Medical Center researchers have uncovered a new mechanism of bone erosion and a possible biomarker for rheumatoid arthritis (RA). The group is the first to demonstrate that immune cells, called B cells, ...

Arthritis & Rheumatism

Osteoarthritis: Carbohydrate-binding protein promotes inflammation

More and more people, particularly older people, are suffering from osteoarthritis due to wear and tear on their joints. This primarily affects the knee and hip joints but also the spine. In earlier studies, scientists at ...

Arthritis & Rheumatism

Incidence of psoriatic arthritis 2.7/100 psoriasis patients

(HealthDay)—The incidence of psoriatic arthritis (PsA) is 2.7 cases per 100 psoriasis patients, with risk factors including severe psoriasis phenotype and low level of education, according to a study published in the April ...

Arthritis & Rheumatism

Phase-3 drug trial for refractory rheumatoid arthritis succeeds

In a pivotal phase-3 trial led by a Stanford University School of Medicine investigator, a novel drug for rheumatoid arthritis substantially reduced symptoms and improved daily physical functioning in patients for whom other ...

Arthritis & Rheumatism

Tocilizumab treats rheumatoid arthritis after non-TNFi failure

(HealthDay)—For patients with rheumatoid arthritis (RA) and a first non-tumor necrosis factor inhibitor (TNFi) failure, treatment with tocilizumab seems more efficacious than abatacept or rituximab, according to a study ...

Arthritis & Rheumatism

Analgesics plus exercise therapy feasible for knee OA

(HealthDay)—A combined intervention of optimized analgesic prescription and exercise therapy is feasible and associated with significant reductions in pain and activity limitation in patients with knee osteoarthritis (OA) ...

Arthritis & Rheumatism

Serotonin deficiency implicated in rheumatoid arthritis

For the first time, serotonin (5-hydroxytryptamine, 5-HT) has been directly implicated in the pathophysiology of rheumatoid arthritis (RA). Although 5-HT is predominantly known as a neurotransmitter within the central nervous ...

Arthritis & Rheumatism

PTSD symptomatology linked to increased risk of RA

(HealthDay)—Posttraumatic stress disorder (PTSD) symptomatology is associated with the risk of rheumatoid arthritis (RA) in women, according to a study published in the March issue of Arthritis Care & Research.

Medical research

Polymer gel effectively reinforces worn out cartilage

Aching knees and stiff fingers: osteoarthritis is a widespread joint disease with few treatment options. However, there may finally be some hope: American scientists are hoping to mechanically reinforce worn-out cartilage ...

Arthritis & Rheumatism

Protein that triggers juvenile arthritis identified

Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person's own tissue. But no "autoantigens"—the ...

Arthritis & Rheumatism

Psoriasis does not worsen total hip arthroplasty outcomes

(HealthDay)—For patients undergoing total hip arthroplasty (THA), neither psoriatic arthritis (PsA) nor cutaneous psoriasis (PsC) are risk factors for poor outcomes, according to a study published in the February issue ...

Arthritis & Rheumatism

Guidelines developed for ankylosing spondylitis treatment

(HealthDay)—Evidence-based recommendations have been developed for treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). The guidelines were published in the February ...

Arthritis & Rheumatism

Compound in green tea found to block rheumatoid arthritis

Researchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, inflammation and tissue damage caused by rheumatoid arthritis.

Arthritis & Rheumatism

Tissue fluid flow can reveal onset of osteoarthritis

Reflecting the overall structural alterations in the tissue, changes in the flow of interstitial fluid in articular cartilage could be an indicator revealing the onset of osteoarthritis, according to a new study from the ...