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Laboratory medicine news

Real-time metabolic monitoring on a chip: What happens inside a cell can be measured instantly

In a significant advancement for lab-on-chip technology, IBEC researchers in the frame of the European project BLOC, have demonstrated the first integration of a benchtop nuclear magnetic resonance (NMR) spectrometer with ...

Detecting Alzheimer's with DNA aptamers—new tool for an easy blood test

With aging populations on the rise, the need for better tools to diagnose and monitor Alzheimer's disease (AD), the most common cause of dementia, has never been more urgent. This disease is characterized by the gradual loss ...

Mpox immune test validated during Rwandan outbreak

An antibody test for the infectious disease mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting. The test, an IgG ELISA ...

HIV-seq tool finds active reservoir cells during therapy

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission. Historically, these ...

Cheek cells may provide clues to schizophrenia risk

A simple cheek swab could one day provide a quick and noninvasive diagnostic test for schizophrenia. A new study published in Science Advances has identified higher levels of two biological markers in the cheek swabs of patients ...

Tiled amplicon sequencing could transform tuberculosis care

When the COVID-19 pandemic was at its peak, and multiple variants were threatening lives around the world, scientists relied on a process called "tiled amplicon sequencing" to track the virus's spread. Now, an international ...

Gallbladder cancer could soon be detected in blood

Researchers at Tezpur University in Assam, India, working with scientists at the University of Illinois Urbana-Champaign, have identified distinct chemical signatures in blood that could help detect gallbladder cancer earlier. ...

Illicit diazepam tablets show wide strength variation

A study from King's, in collaboration with TICTAC Communications and Nanalysis, tested seized tablets containing the sedative diazepam and found considerable variation in strength and content, highlighting the dangers of ...

When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

Pattern of chronic rejection for liver transplants decoded

Liver transplants often save the lives of seriously ill patients. However, there remains a risk that the body will reject the new organ. Doctors distinguish between acute and chronic rejection. While acute rejection is easy ...

AI tool spots blood cell abnormalities missed by doctors

An AI tool that can analyze abnormalities in the shape and form of blood cells, and with greater accuracy and reliability than human experts, could change the way conditions such as leukemia are diagnosed.

Molecule that could cause COVID clotting key to new treatments

In a surprising discovery, a "sticky molecule" that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new treatments to counter COVID-related ...