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Oncology & Cancer news

Oncology & Cancer

Chronic stress accelerates colorectal cancer progression by disrupting the balance of gut microbiota, study shows

Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.

Oncology & Cancer

Dense breasts can make it harder to spot cancer on a mammogram

When a woman has a mammogram, the most important finding is whether there's any sign of breast cancer.

Oncology & Cancer

An AI-powered pipeline for personalized cancer vaccines

Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular targets of T cells and harnesses ...

Oncology & Cancer

Long-term study shows early prostate cancer surgery extended life

The survival rate of men with prostate cancer who had their entire prostate gland removed immediately after the tumor was detected increased by 17 percentage points compared with those who did not have treatment until the ...

Oncology & Cancer

Study uncovers mutations and DNA structures driving bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center. The researchers found that antiviral enzymes that mutate ...

Oncology & Cancer

Risk of side effects from cancer immunotherapy linked to genetics

Even as they've revolutionized cancer treatment, drugs known as immune checkpoint inhibitors can produce a range of adverse, immune-related side effects. In a new study, scientists at Dana-Farber Cancer Institute identify, ...

Oncology & Cancer

Researchers expanding the types of cancer CAR-T therapy can target

Teaching the body's immune cells to recognize and fight cancer is one of the holy grails in medicine. Over the past two decades, researchers have developed new immunotherapy drugs that stimulate a patient's immune cells to ...

Oncology & Cancer

Killing pancreatic cancer with T cells that supercharge themselves

Scientists at UC San Francisco (UCSF) have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells. The immunotherapy eliminated melanoma and pancreatic cancer in mice without ...

Oncology & Cancer

Examining resistance to immunotherapy in ovarian cancer

A team at Memorial Sloan Kettering Cancer Center (MSK) has uncovered several mechanisms of immune escape that can help explain why ovarian cancers have been resistant to immunotherapy to date.

Oncology & Cancer

New targets in the fight against pancreatic cancer

Pancreatic cancer remains one of the deadliest malignancies worldwide. Since five-year survival rate for pancreatic ductal adenocarcinoma (PDAC) is only about 3% in patients, PDAC is very difficult to treat with surgery worldwide. ...

Oncology & Cancer

Reconsidering oxygen's role in growth of tumors

Yale researchers have made a discovery that changes conventional thinking about the role that oxygen plays in the growth of tumors—an area of cancer research that has been intensely studied in recent years.