Combination therapy shows promise in subset of breast cancers
Combining two cancer drugs may be a promising treatment for advanced metastatic breast cancer, according to the results of a clinical trial published in JAMA Oncology.
Jun 17, 2024
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Amino Acid, Peptide, or Protein: Trastuzumab
Medical news and research articles
New platform streamlines epitope comparison in antibody research
Monoclonal antibodies are crucial therapeutics due to their high specificity and binding affinity for epitopes (the precise sites where an antibody attaches itself to an antigen, triggering an immune response). Since the ...
Jun 10, 2024
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Drug resistance discovery could 'move the field forward' for breast cancer treatment
Research recently published in Drug Resistance Updates has revealed a previously unknown biological process through which breast tumor cells develop resistance to standard treatment, which could open the door for cancer scientists ...
May 29, 2024
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Understanding what causes trastuzumab's cardiotoxicity
A new meta-analysis published in OMICS: A Journal of Integrative Biology helps shed light on how changes in mitochondria-related gene expression may cause the cardiotoxicity associated with the cancer therapy trastuzumab.
Mar 18, 2024
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Mathematical model mimics vascular tumor growth in breast cancer and its response to treatment
Choosing the right cancer treatment is a massive undertaking involving multiple stages, high experimental complexity and significant costs. Currently, two main methods are used to find the best possible treatment solutions: ...
Jan 16, 2024
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Study: Pembrolizumab + chemo, trastuzumab beneficial in gastroesophageal cancer
For patients with HER2-positive gastroesophageal junction (GEJ) adenocarcinoma, pembrolizumab improves progression-free survival when combined with chemotherapy and trastuzumab, according to a study published online Oct. ...
Oct 25, 2023
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Significant discovery in breast cancer research: Inhibiting collagen XVIII function weakens cancer cells
Researchers at the University of Oulu have made a discovery in breast cancer research. They demonstrated that the extracellular matrix protein collagen XVIII significantly promotes breast cancer progression and metastasis. ...
Oct 17, 2023
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Oncology drugs estimated to be $1 billion cheaper to develop through a precision approach
Research and development (R&D) costs for targeted oncology drugs are markedly lower if guided by a companion diagnostic strategy, but current biopharmaceutical business models suggest these savings will not be reflected in ...
Aug 21, 2023
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Breast cancer patients with higher BMI more likely to experience heart damage during chemotherapy, study finds
Breast cancer survival rates have improved considerably in the last few decades in Colombia, but factors that increase the likelihood of patients experiencing cardiovascular side effects, like cardiotoxicity, are not well-known ...
Aug 2, 2023
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Biosimilars drug market isn't broken after all, study finds
The U.S. biosimilar drug market emerged in 2015 to provide safe, effective, and more affordable alternatives to existing biologic drugs, but it has been slow to develop compared with Europe.
Jun 6, 2023
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