The TREM2 antibody: A new player in atherosclerosis
A new study has investigated the mechanisms by which the receptor TREM2 affects atherosclerosis and a possible therapeutic approach using an agonistic TREM2 antibody.
Mar 12, 2024
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Amino Acid, Peptide, or Protein: TREM2 protein, human
Medical news and research articles
Study identifies new pathway to combat primary cause of cardiovascular disease
Research led by the University of Minnesota Medical School identified a new pathway to combat cardiovascular disease. The study was recently published in Nature Cardiovascular Research.
Nov 3, 2023
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Researchers find success with stem cell therapy in mice model of Alzheimer's disease
Stanford Medicine researchers are hopeful that a proof-of-concept treatment in mice—blood stem cell transplants—may reduce signs of Alzheimer's disease.
Sep 22, 2023
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Researchers identify several new genetic risk factors for Alzheimer's disease unique to Ashkenazi Jews
Alzheimer's disease (AD), the most common neurodegenerative disorder in the world, affects individuals of all races and ethnicities; however, most genetic research for AD has been performed on individuals of European ancestry ...
Jun 1, 2023
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Sleep deprivation is a risk factor for Alzheimer's, say scientists who turned to animal models to find out why
Scientists have long explored the link between disturbances in sleep patterns and neurodegenerative diseases. Powerful evidence has emerged in recent years linking disrupted sleep to Parkinson's, and a massive body of research ...
Antitumor cell activity in glioblastoma regulated by inhibiting triggering receptor expressed on myeloid cells 2
While the importance of the triggering receptor expressed on myeloid cells 2 (TREM2) is known in brain microglial function during neurodegenerative diseases, the function of the TREM2 cell receptor/protein is unknown in glioblastoma ...
New lung immuno-oncology therapeutic strategy identified
Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated in a preclinical study a potential new therapeutic approach to treating the most common form of lung cancer.
Apr 20, 2023
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A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia
The protein TREM2, which in humans is encoded by the TREM2 gene, is known to play a crucial role in the growth and development of different types of immune cells, including microglia. Microglia are specialized immune cells ...
Immunologists uncover obesity-linked trigger to severe form of liver disease
UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure. The finding, published in Immunity, could ...
Dec 27, 2022
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The brain's immune cells can be triggered to slow down Alzheimer's disease, study shows
The brain's big-eating immune cells can slow down the progression of Alzheimer's disease. This is shown by a study that is now published in Nature Aging.
Nov 29, 2022
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