As recently as the mid-20th century, aging was described by Nobel Prize laureate Peter Medawar as "an unsolved problem in biology." Today, scientists can analyze the activity of thousands of genes in individual cells, identify ...
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Huntington disease is a rare, inherited brain disorder that progressively destroys nerve cells, leading to worsening movement, cognitive and psychiatric symptoms. Caused by a mutation in the huntingtin gene, the fatal disease ...
Jun 8, 2026
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Rugby league player Jai Arrow's recently announced diagnosis of motor neuron disease has again brought this devastating disease to public attention.
May 22, 2026
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Why do cells age—and why do we lose our energy and vitality as we get older? This question is one of the central challenges of modern biomedicine. The focus is particularly on mitochondria—tiny cellular organelles long known ...
May 21, 2026
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By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the burden of age-related diseases, particularly Alzheimer's disease ...
May 5, 2026
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What began as research aimed at expanding the limited treatment options for cystinuria, a rare genetic disorder affecting 1 in every 7,000 people, characterized by the recurrent formation of cystine stones in the kidneys ...
Apr 21, 2026
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Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have developed MitoCatch, a system that enables targeted delivery of healthy mitochondria to specific cell types affected ...
Apr 15, 2026
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Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship—but mitochondria brought some baggage. ...
Apr 6, 2026
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Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial dysfunction has been recognized as a hallmark of exhausted T cells in tumors. Yet how metabolic stress ...
Mar 18, 2026
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Human cells have two copies of each chromosome, and this balance is essential for genes to be expressed in the appropriate proportions and for cells to function correctly. When errors occur during cell division and the number ...
Mar 17, 2026
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