Ciliopathies are multisystem disorders characterized by the dysfunction of motile and/or non-motile cilia, which show common clinical manifestations of ciliopathies include retinal degeneration, mental retardation, renal ...
Jun 7, 2024
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Scientists from Duke-NUS Medical School have identified a gene that plays a crucial role in regulating energy supply to cells that drive kidney failure. This discovery concerning the gene named WWP2 offers a new target for ...
Mar 21, 2024
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Chronic kidney disease (CKD) affects 10% of the global population, among which renal fibrosis is a progressive process that can lead to end-stage renal failure. Early diagnosis and active monitoring are particularly important.
Mar 14, 2024
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Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in Science, could lead to the development ...
Feb 22, 2024
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Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following ...
Nov 22, 2023
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Kidney organoids provide a promising platform in vitro to model the mechanisms of kidney disease, however, they are limited by an existing lack of knowledge of their inherent functional protein expression. In a new report ...
Fresh insights into a protein that causes damage in kidneys and hearts could open up new treatment options for chronic kidney disease, research shows.
May 31, 2023
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Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis. The group's findings, reported in Cell Death & Disease, suggest ...
Mar 23, 2023
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A serious condition that can cause the kidneys to suddenly stop working could be treated with existing medicines, a new study shows.
Dec 14, 2022
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Webster Santos is determined to find a way to halt kidney fibrosis, a condition caused by persistent inflammation and assault to the kidney. The disorder leads to kidney disease, itself a pathway to kidney failure, also known ...
Aug 22, 2022
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