DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown that one such structure, ...
Feb 7, 2026
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The onset and aggressiveness of cancer are related to the abnormal behavior of certain genes, known as oncogenes. The best-known of these alterations is mutation, but it is not the only one. Sometimes, within a cell, a very ...
Feb 6, 2026
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UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer. ...
Feb 4, 2026
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Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons are mobile DNA pieces, ...
Jan 5, 2026
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Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through generations, Stanford Medicine-led ...
Dec 2, 2025
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Could a natural check on cancer be used to stop the disease? It's possible, but to leverage a system that nature designed, we must first understand it. Researchers led by a team at Purdue University are exploring a molecular ...
Aug 27, 2025
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Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor.
Jul 9, 2025
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Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the patient will experience a recurrence years after their initial diagnosis.
Feb 10, 2025
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Researchers have long known that there is a relationship between the cancer-associated gene MYC (pronounced "Mick") and exercise adaptation. When human muscles are exercised, MYC is found to increase transiently in abundance ...
Dec 3, 2024
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A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles—until recently dismissed as inconsequential—are major drivers ...
Nov 6, 2024
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