Researchers have long known that there is a relationship between the cancer-associated gene MYC (pronounced "Mick") and exercise adaptation. When human muscles are exercised, MYC is found to increase transiently in abundance ...
Dec 3, 2024
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A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles—until recently dismissed as inconsequential—are major drivers ...
Nov 6, 2024
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Cancer is caused by genetic changes that occur in our cells over time. There are two main types of changes, namely somatic mutations, which are alterations in the DNA sequence, and copy number alterations, which are changes ...
Jul 23, 2024
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A study led by Pompeu Fabra University describes the mechanism whereby insulinomas, a rare type of neuroendocrine tumor that affects pancreatic beta cells, form. According to the study, insulinomas are the result of the accumulation ...
Jul 2, 2024
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Many people are familiar with oncogenes—genes long known to be involved in cancers in humans, such as the gene Src. What's less widely understood is that oncogenes didn't evolve just to cause cancer in species, but rather ...
Jun 24, 2024
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A Stanford Medicine study of thousands of breast cancers has found that the gene sequences we inherit at conception are powerful predictors of the breast cancer type we might develop decades later and how deadly it might ...
May 30, 2024
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Graduate student Hillary Layden studies transcriptional control of cancer in the lab of Scott Hiebert, Hortense B. Ingram Chair in Cancer Research and professor of biochemistry.
May 30, 2024
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A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three ...
Nov 14, 2023
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Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...
Oct 6, 2023
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While cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at Dana-Farber and the Broad Institute of MIT and Harvard have found that gliomas—incurable brain tumors—can ...
Jul 25, 2023
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