Two recent studies from the University of California, Riverside, published in the same issue of Gut Microbes highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel ...
Jan 24, 2026
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Chimeric Antigen Receptor (CAR) T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers. Solid tumors, which account for around 90% of all adult cancers, remain ...
Nov 4, 2025
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By stimulating macrophages—a type of white blood cell—with biological factors that mimic infection, researchers have uncovered genetic drivers of complex diseases such as inflammatory bowel disease (IBD), in one of the largest ...
Aug 27, 2025
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A study led by biomedical scientists at the University of California, Riverside School of Medicine shows how a genetic mutation associated with Crohn's disease can worsen iron deficiency and anemia—one of the most common ...
Jun 8, 2025
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There is an urgent need for precision immunotherapy strategies that simultaneously target both tumor cells and immune cells to enhance treatment efficacy. Identifying genes with dual functions in both cancer and immune cells ...
Apr 1, 2025
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Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus's ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.
Jan 14, 2025
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In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances. But while immunotherapy drugs offer new treatment possibilities, only about 20% to 40% of patients respond ...
Apr 11, 2024
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Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer. As researchers have learned more and more about the cancer-immune system interplay, several antitumor immunotherapies ...
Feb 28, 2024
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Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.
Nov 14, 2023
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Inflammatory bowel disease, or IBD, describes Crohn's disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune ...
Apr 7, 2023
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