Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious problems for cells. Surprisingly, the opposite is also true: Cells can become highly resistant ...
May 30, 2026
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The human body cannot produce vitamin B2—also known as riboflavin—itself; it must absorb the important substance through diet. The vitamin can be found in dairy products, eggs, meat and green vegetables. The metabolism converts ...
Mar 13, 2026
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NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.
Nov 5, 2025
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Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a surprising metabolic dependency that could open the door to a new class of cancer ...
Nov 5, 2025
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A new research paper titled "Targeting of FSP1 regulates iron homeostasis in drug-tolerant persister head and neck cancer cells via lipid-metabolism-driven ferroptosis" has been published in Aging.
Jan 24, 2024
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A research team at Helmholtz Munich has revealed a specific mechanism that is able to promote cell death in cancer cells by pharmacological targeting of a ferroptosis surveillance system.
Jul 5, 2023
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A team of researchers led by Dr. Marcus Conrad from Helmholtz Munich has discovered a novel anti-cancer drug called icFSP1, which sensitizes cancer cells to ferroptosis. The results of this research are published in Nature.
Jun 28, 2023
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All human tumors originating from various tissues share a series of properties that define them, including the ability to prevent cell death. Instead, healthy organs induce programmed cell death or apoptosis to balance their ...
Aug 1, 2022
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