A new study led by researchers at the University of California San Diego School of Medicine suggests that an experimental gene therapy could help protect the brain from the damage and cognitive decline linked to TDP-43-related ...
May 26, 2026
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Dementia affects over 57 million people worldwide, a number expected to nearly double in the next 20 years. This permanent loss of cognitive abilities affects daily function and can be caused by multiple brain pathologies, ...
May 10, 2026
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Misshapen proteins cause a mess of trouble—particularly in neurodegenerative diseases. But a new study suggests it's possible that giving them a little bit of extra support could keep them working correctly, and even reverse ...
May 8, 2026
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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes the progressive loss of motor neurons, which in most cases leads to respiratory failure within three to five years after diagnosis. In this context, ...
Apr 30, 2026
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Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms, characterized by muscle wasting, paralysis, dementia, and other serious impairments. ...
Mar 12, 2026
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A Northwestern Medicine study has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS), according to findings published in the journal Neuron.
Dec 15, 2025
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Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are medical conditions characterized by the progressive degradation of cells in the brain, ...
The two neurodegenerative diseases could not appear more different. Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig's disease, affects the muscles, ultimately paralyzing people with the disorder. Frontotemporal ...
Nov 27, 2025
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Jijing Wang, Ph.D., and Hyun-Sik Yang, MD, of the Department of Neurology at Mass General Brigham, are the lead and senior authors of a paper published in Molecular Neurodegeneration titled "Plasma TDP-43 is a potential biomarker ...
Nov 20, 2025
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A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral ...
Oct 31, 2025
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