Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting pathogenesis features neuroinflammation, ...
Feb 12, 2024
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In the development of Parkinson's disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms. But without a test that can detect these changes, it's difficult ...
Jan 8, 2024
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Grégoire Courtine, Jocelyne Bloch and their research team have been breaking new ground in the treatment of neurological disorders for over a decade. Here's a look at some of the promising new therapies they've developed.
Jan 8, 2024
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Early one morning, while checking on a slumbering patient at the Center for Sleep Medicine, Erik St. Louis, M.D., noticed something peculiar. The patient, a woman in her early 60's, had started running beneath her bedsheets. ...
Aug 28, 2023
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A little-known and poorly understood sleep disorder that occurs during the rapid eye movement, or REM, stage of sleep has been garnering attention for its role in foreshadowing neurodegenerative brain diseases such as Parkinson's ...
May 26, 2023
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A University of Massachusetts Amherst scientist has discovered that a mutation in the misfolding protein that causes Parkinson's disease offers protection against another fatal neurodegenerative disorder—multiple system atrophy ...
Dec 1, 2022
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Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by the aggregation of α-synuclein in the brain. Now, scientists from Japan, in collaboration with three pharmaceutical companies, have developed ...
Aug 30, 2022
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