Medications

ECT more effective than ketamine in severe depression

Researchers at Lund University in Sweden have compared the effects of intravenous ketamine treatment with ECT (electroconvulsive therapy) treatment in severe depression. The results support the view that ketamine is a possible ...

Psychology & Psychiatry

Why severe depression affects women and men differently

A team of Université Laval scientists may have discovered why severe depression affects women and men differently, according to a study published today in Nature Communications. The researchers examined the brains of people ...

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Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behaviour, feelings and physical well-being. Depressed people may feel sad, anxious, empty, hopeless, helpless, worthless, guilty, irritable, or restless. They may lose interest in activities that once were pleasurable, experience loss of appetite or overeating, or problems concentrating, remembering details or making decisions; and may contemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss of energy, or aches, pains or digestive problems that are resistant to treatment may be present.

Depressed mood is a normal reaction to certain life events, a symptom of some medical conditions (e.g., Addison's disease, hypothyroidism), various medical treatments (e.g., hepatitis C drug therapy), and a feature of certain psychiatric syndromes.

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