An international team including Charité Universitätsmedizin Berlin, Soongsil University, and Sungkyunkwan University has found that Korean adults living alone with both depression and anxiety face a 558% increased risk ...
Researchers at Zhejiang University found that acute stress increases natural repair mechanisms in the brain, while chronic stress suppresses them. Autophagy was most affected in the lateral habenula, a brain region linked ...
Major depressive disorder (MDD) affects approximately 280 million people globally and is one of the leading causes of disability and low quality of life. One in every three people suffering from MDD also has to deal with ...
Copenhagen University Hospital–Rigshospitalet and collaborating Danish universities have conducted statistical research suggesting that starting hormonal contraceptive (HC) use postpartum is associated with a 49% higher ...
Chronic pain—or pain that lasts at least three months—is closely intertwined with depression. Individuals living with pain's persistent symptoms may be up to four times more likely to experience depression, research shows.
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Patients with depression who received the Moodivate app saw clinically meaningful reductions in their symptoms that were twice those achieved with standard-of-care therapy in a clinical trial conducted at 22 primary care ...
Apr 14, 2025
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Childhood maltreatment (CM) is a complex issue that is often passed on through generations. Studies have shown that parents who were abused as children may perpetuate a similar pattern of mistreating their children, creating ...
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Although a plethora of medications and therapies now exist for major depression, roughly one in three diagnosed patients still suffer from treatment-resistant depression (TRD)—a form of the disorder that does not respond ...
Apr 3, 2025
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Excessive screen time among adolescents negatively impacts multiple aspects of sleep, which in turn increases the risk of depressive symptoms—particularly among girls. That is the conclusion of a new study in PLOS Global ...
Apr 2, 2025
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Dartmouth researchers conducted the first clinical trial of a therapy chatbot powered by generative AI and found that the software resulted in significant improvements in participants' symptoms, according to results published ...
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Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behaviour, feelings and physical well-being. Depressed people may feel sad, anxious, empty, hopeless, helpless, worthless, guilty, irritable, or restless. They may lose interest in activities that once were pleasurable, experience loss of appetite or overeating, or problems concentrating, remembering details or making decisions; and may contemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss of energy, or aches, pains or digestive problems that are resistant to treatment may be present.
Depressed mood is a normal reaction to certain life events, a symptom of some medical conditions (e.g., Addison's disease, hypothyroidism), various medical treatments (e.g., hepatitis C drug therapy), and a feature of certain psychiatric syndromes.
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