Oncology & Cancer

Primary hepatic angiosarcoma: Treatment options for a rare tumor

In an editorial, researchers Gregory L. Guzik and Ankit Mangla from University Hospitals Cleveland Medical Center, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, and Case Comprehensive ...

Oncology & Cancer

Improving the conversion success rate of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) presents significant challenges due to its high incidence and mortality rates, particularly in China where most patients are diagnosed at intermediate or advanced stages. This limits the applicability ...

Oncology & Cancer

New thesis on biomarkers for hepatocellular carcinoma

Robin Zenlander from the Gastroenterology and Rheumatology Unit at the Department of Medicine, Huddinge, is defending his thesis titled "Biomarkers in hepatocellular carcinoma," on 13 June, 2024.

Health informatics

Deep leaning technology shows potential in photodynamic therapy

In contrast to traditional cancer treatments such as surgery, chemotherapy, and radiotherapy, photodynamic therapy (PDT) is emerging as a novel method that uses specific wavelengths of light to activate photosensitizers. ...

Medications

Combined therapy makes headway for liver cancer

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a phase two ...

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Hepatocellular carcinoma (HCC, also called malignant hepatoma) is the most common type of liver cancer. Most cases of HCC are secondary to either a viral hepatitide infection (hepatitis B or C) or cirrhosis (alcoholism being the most common cause of hepatic cirrhosis).

Compared to other cancers, HCC is quite a rare tumor in the United States. In countries where hepatitis is not endemic, most malignant cancers in the liver are not primary HCC but metastasis (spread) of cancer from elsewhere in the body, e.g., the colon. Treatment options of HCC and prognosis are dependent on many factors but especially on tumor size and staging. Tumor grade is also important. High-grade tumors will have a poor prognosis, while low-grade tumors may go unnoticed for many years, as is the case in many other organs, such as the breast, where a ductal carcinoma in situ (or a lobular carcinoma in situ) may be present without any clinical signs and without correlate on routine imaging tests, although in some occasions it may be detected on more specialized imaging studies like MR mammography.

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