The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
Next-generation sequencing studies have in recent years revealed numerous recurrently mutated genes in chronic lymphocytic leukemia (CLL). These mutations are usually found in a relatively small percentage of cases and associated ...
Mar 3, 2023
0
86
The latest research from SAHMRI and the University of Adelaide has discovered a potential new therapy for chronic myeloid leukemia (CML) patients who've achieved excellent results from current treatment and are hoping to ...
Mar 1, 2023
0
2
Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone. Venetoclax is a new targeted therapy option for the treatment of ...
Feb 23, 2023
0
38
In elderly adults aged 60 years and older with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS), allogeneic hematopoietic stem cell transplant (HSCT) can be performed with acceptable overall survival and nonrelapse ...
Feb 21, 2023
0
3
An international team of medical scientists has found more evidence of infections in pregnant women raising the risk of leukemia developing in babies. In their paper published in JAMA Network Open, the group analyzed data ...
Residing in border regions was linked with a higher risk of dying within five years among children with acute lymphoblastic leukemia, the most common type of pediatric cancer.
Feb 21, 2023
0
40
Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant ...
Feb 16, 2023
0
37
Acute myeloid leukemia (AML) is an aggressive form of cancer that originates in the bone marrow, rapidly spreads to the blood, and can quickly cause death if not treated promptly. Despite recent therapeutic advances, it continues ...
Feb 7, 2023
0
22
In 2022, an estimated 7,000 Canadians were diagnosed with leukemia, a term used to define cancer of the blood cells. Of that 7,000, it is estimated that nearly half will face mortality. University of Saskatchewan (USask) ...
Feb 7, 2023
0
5