A new research paper titled "MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway" has been published in Oncotarget.
Nov 10, 2022
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Social determinants of health affect the outcomes of many illnesses, and pediatric cancer is no exception. In fact, children with acute lymphoblastic leukemia (ALL) living in poverty are significantly more likely to relapse ...
Nov 10, 2022
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Northwestern Medicine investigators have discovered the mechanisms by which a particular protein promotes cancer cell proliferation and survival in acute myeloid leukemia (AML), according to a Northwestern Medicine study ...
Nov 4, 2022
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For years, brand drug companies have been villainized for "evergreening" or manipulating the law to extend the period of exclusivity for drugs beyond their 20-year patent—a practice critics say unfairly prevents competition ...
Nov 3, 2022
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Patients with acute myeloid leukemia, the most common type of adult blood cancer, show large-scale genomic mutations and altered DNA folding patterns that could help identify potential therapeutic targets, according to a ...
Oct 28, 2022
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Endothelial cells—the cells that line blood vessels—grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study by Weill Cornell Medicine investigators found.
Oct 19, 2022
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Babies with leukemia could get an array of new treatments after scientists used genetic engineering to reproduce a gene defect found in the disease.
Oct 7, 2022
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In work published in Leukemia Research, University of Minnesota Medical School researchers explored the possible biological mechanisms that could explain the association between being overweight or obese prior to pregnancy ...
Sep 28, 2022
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Many drug-resistant tumors have dysfunctional metabolism of ceramide, a metabolite that promotes cell death.
Sep 21, 2022
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Elective cesarean section (CS) is associated with an increased risk for leukemia in offspring, according to a systematic review and meta-analysis published online Aug. 24 in Hematological Oncology.
Sep 15, 2022
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