A new study will enable clinicians to identify patients with aggressive leukemia who will not respond to chemotherapy and those who are most likely to benefit from a new immunotherapy.
Jun 5, 2020
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Researchers at Mount Sinai have discovered that human acute myeloid leukemia (AML) stem cells are dependent on a transcription factor known as RUNX1, potentially providing a new therapeutic target to achieve lasting remissions ...
Jun 2, 2020
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706
Hematopoietic stem cells from a healthy donor can help patients suffering from acute leukemia. However, the side effects of therapies are often severe. A group of researchers led by the University of Zurich have now shown ...
May 8, 2020
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44
Drug resistance is a major obstacle in cancer treatment—leading to relapse for many patients. In a new study, published online April 20, 2020, in Nature Cell Biology, researchers from the Stowers Institute for Medical Research, ...
Apr 21, 2020
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174
A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains ...
Apr 20, 2020
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267
New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels ...
Mar 30, 2020
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90
Children with aggressive blood cancers have differences—not just in the DNA code of their blood cells—but also in the heavily twisted protein superstructure that controls access to genes.
Mar 23, 2020
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134
St. Jude Children's Research Hospital scientists have discovered a gene associated with about half of glucocorticoid resistance in children with the most common pediatric cancer. Researchers have also identified a drug that ...
Mar 9, 2020
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101
Acute myeloid leukemia (AML), a blood cancer affecting both adults and children, requires more than one genetic "hit" to develop. As we age, many of us acquire a mutation that enables certain of our blood cells to multiply ...
Feb 14, 2020
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340
A genetic mutation that disrupts how DNA sends messages to the rest of a cell has been linked to a large number of blood cancers. Thanks to a collaboration between biologists at Cold Spring Harbor Laboratory (CSHL) and an ...
Jan 31, 2020
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