Oncology & Cancer
Five things to know about melanoma
"Five things to know about ... melanoma" in CMAJ (Canadian Medical Association Journal) provides a brief overview of this malignant skin cancer for physicians and patients.
May 13, 2019
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22
Melanoma
Oncology & Cancer
Researchers find BRAF protein modification could slow tumor growth
The protein BRAF is a key player in the development of many different types of cancer, including melanoma. Scientists have known that BRAF becomes activated by growth factors and subsequently stimulates downstream proteins ...
Apr 24, 2019
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8
Oncology & Cancer
Researchers identify mechanism of resistance to BRAF inhibitors in melanoma
Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, ...
Apr 15, 2019
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3
Oncology & Cancer
Is your melanoma hot enough for immunotherapy?
Melanomas tend to be "hot" or "cold—if they're hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, ...
Apr 3, 2019
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3
Oncology & Cancer
Study may explain why immunotherapy not effective for some patients with metastatic melanoma and kidney cancer
White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson ...
Mar 25, 2019
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2
Oncology & Cancer
Researchers discover therapeutic target of melanoma
Researchers have identified a biomarker and a possible new therapy for melanoma.
Mar 25, 2019
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109
Oncology & Cancer
Nuclear medicine imaging monitors effectiveness of therapy for melanoma patients
Nuclear medicine imaging with PET/CT can monitor the effectiveness of immunotherapy treatment for metastatic melanoma and predict outcome. In this way, a patient's therapy can be more effectively tailored to his or her personal ...
Mar 5, 2019
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4
Oncology & Cancer
New studies aim to improve melanoma diagnosis
A pair of studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers could aid in improved diagnosis for melanoma, the deadliest form of skin cancer.
Mar 5, 2019
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6
Oncology & Cancer
Genomic testing of a single patient reveals a gene commonly mutated in pediatric melanoma
Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma. The St. Jude Children's ...
Mar 4, 2019
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55
Oncology & Cancer
Physical combination multiplies melanoma risk
The risk of developing melanoma is significantly multiplied for people who have red hair and more than 20 large moles, University of Queensland researchers have found.
Mar 4, 2019
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