Scientists find a region of mouse gut tightly regulated by the immune system
The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions ...
10 hours ago
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People with chronic liver disease can be categorized into four distinct risk groups, study finds
People with chronic liver disease can be categorized into four distinct risk groups based on the different barriers they face in obtaining outpatient care, barriers that increase their odds of requiring hospitalization, a ...
11 hours ago
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Scientists identify molecule that promotes gut regeneration and limits tumor growth
Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer. The discovery could lead to new treatments for inflammatory ...
14 hours ago
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Ingestible capsule can pump drugs directly into the walls of the GI tract
Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into ...
14 hours ago
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Combining 25 datasets, researchers map 1.6 million gut cells to find new ways treat disease
The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.
14 hours ago
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Extracellular vesicles may be key to developing safer and more effective therapies for inflammatory bowel disease
Researchers at Germans Trias i Pujol Research Institute (IGTP) and Institut d'Investigació Sanitària Pere Virgili (IISPV) have conducted a review on the therapeutic potential of extracellular vesicles in inflammatory bowel ...
8 hours ago
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Gastroenterology education improved through inpatient care teaching model
Gastroenterologists who focus primarily on providing inpatient care, called GI Hospitalists, are becoming more common across the U.S. Researchers at Brigham and Women's Hospital developed a survey to assess the effect of ...
11 hours ago
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Assessment reveals more than 100,000 American youth living with inflammatory bowel disease
A study published today in Gastroenterology provides the most comprehensive assessment to date of pediatric inflammatory bowel disease (IBD) prevalence in the United States.
13 hours ago
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Study links phosphate levels to kidney damage markers
Researchers at University of Tsukuba have found that the phosphate concentration in proximal tubule fluid, estimated from urine and blood tests, is associated with elevated renal tubular damage markers.
Nov 19, 2024
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Gastroesophageal reflux disease linked to cardiovascular risk factors: New insights from Mendelian randomization study
A recent study published in the Journal of Translational Internal Medicine reveals insights into the broader impact of gastroesophageal reflux disease (GERD) on cardiovascular health. By using a rigorous bidirectional Mendelian ...
Nov 19, 2024
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Clinical guideline for moderate-to-severe ulcerative colitis released
The American Gastroenterological Association (AGA) has released a new clinical guideline on the pharmacological management of moderate-to-severe ulcerative colitis, published in Gastroenterology.
Nov 19, 2024
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Experimental oxytocin-based drug offers new hope for gut disorders
University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions.
Nov 18, 2024
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Microbiome changes in chronic liver disease highlight need for personalized treatment
The bacterial changes also correlate with increased antibiotic resistance, highlighting the need for better targeting of antibiotic treatment.
Nov 18, 2024
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Bloated after that holiday meal? what's normal, what's not
As the holidays approach, most folks are familiar with a common side effect of the overindulgence that can come with all those meals with family and friends: Bloating.
Nov 17, 2024
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Protein in soy may reduce the risk of heart failure by affecting gut bacteria
A research team from the Nagoya University Graduate School of Medicine has discovered a promising way to slow the progression of heart failure in mice. They fed mice a diet rich in the soybean protein, β-conglycinin (β-CG), ...
Nov 14, 2024
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Scientists develop new method to isolate 'IgA-coated' gut bacteria that are associated with a variety of diseases
Scientists at UMC Utrecht have developed a new technology to efficiently isolate a specific subset of gut bacteria from fecal samples that are recognized by IgA antibodies. These "IgA-coated" bacteria are associated with ...
Nov 14, 2024
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A new screening tool improves liver cancer detection
Hepatocellular carcinoma, a type of liver cancer, is the sixth most common cancer worldwide and the third leading cause of cancer-related deaths. Screening efforts for this cancer focus on individuals diagnosed with viral ...
Nov 14, 2024
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Machine learning study questions gut bacteria–disease link
Many bacterial-linked illnesses, such as inflammatory bowel disease or colorectal cancer, are associated with an overgrowth of gut bacteria thought to be bad actors. But when researchers used a machine learning algorithm ...
Nov 13, 2024
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One-time gene therapy reverses liver disease MASH in mouse models
UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver disease associated with obesity and type 2 diabetes that affects more than 40 million people. The ...
Nov 13, 2024
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Children's gut bacteria may hold the key to diarrhea treatment
Diarrhea claims the lives of 500,000 children each year in low- and middle-income countries. Now, Danish and Ethiopian researchers have linked chronic diarrhea to a specific pattern of gut bacteria, a discovery that could ...
Nov 13, 2024
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Could a genetic flaw be the key to stopping people craving sugary treats?
A study published in Gastroenterology provides novel genetic insights into dietary preferences and opens the possibility of targeting SI to selectively reduce sucrose intake at the population level.
Nov 12, 2024
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Goblet cells could be the guardians of the gut
In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells—specialized cells that line the gut—in maintaining a healthy and balanced immune ...
Nov 12, 2024
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Gut microbiome dynamics linked to rheumatoid arthritis progression
University of Leeds-led research has identified specific changes in the gut microbiome of individuals at risk of rheumatoid arthritis, potentially discovering disease onset mechanisms.