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Gastroenterology news
Immunology
Intestinal immune system gives new clues to mechanism behind food tolerance and allergies
With every bite of food we take, our intestinal immune system must make a big decision. Tasked with defending us from foreign pathogens, these exquisitely sensitive cells somehow distinguish friend from foe—destroying invaders ...
6 hours ago
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Oncology & Cancer
Clinical trial shows fecal microbiota transplantation could help patients heal after stem cell transplantation
A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood cancers.
7 hours ago
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Q&A: Researchers discuss exploring gastric cancer risk through oral microbiomes
Gastric cancer, also known as stomach cancer, is a type of cancer that starts in the stomach lining. Detecting the disease early can improve outcomes, but current methods are often invasive. A new study has found that the ...
7 hours ago
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Exploring irritable bowel syndrome: A common disorder with complex gut-brain interactions
Bowel movements, bloating, and other digestive issues may not be the easiest topics to discuss with your doctor, but having a conversation is the first step to improving your quality of life says Laurence Bailen, a gastroenterologist ...
9 hours ago
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What's the difference between a food allergy and an intolerance?
At one time or another, you've probably come across someone who is lactose intolerant and might experience some unpleasant gut symptoms if they have dairy. Maybe it's you—food intolerances are estimated to affect up to ...
9 hours ago
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Aromatic plant can fight colorectal cancer, say scientists
Scientists from the University of Sharjah have found that a naturally growing aromatic plant contains ingredients with the ability to treat colorectal cancer.
Jan 27, 2025
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Genetic risk factor for Crohn's disease influences natural microbiome changes during pregnancy, mouse study finds
Pregnancy is accompanied by profound changes in the body. Among other things, these affect the energy metabolism and the immune system. But the gut microbiome, i.e., the composition of the microbial community in the gut, ...
Jan 27, 2025
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Guidance developed for diagnosis, management of eosinophilic esophagitis
In a clinical guideline issued by the American College of Gastroenterology and published in the January issue of the American Journal of Gastroenterology, recommendations are presented for the diagnosis and management of ...
Jan 24, 2025
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'Non-industrialized' style diet can reduce risk of chronic disease
Researchers have found that a newly developed diet inspired by the eating habits of non-industrialized societies can significantly reduce the risk of a number of chronic diseases—and plan to share recipes with the public.
Jan 23, 2025
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Study reveals unique features of early-onset colorectal cancer in racial and ethnic minorities
Colorectal cancer is typically diagnosed after age 50, but in recent years the disease has been increasingly found in younger people and disproportionately affecting racial and ethnic minorities.
Jan 23, 2025
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Research identifies gut microbes that offer potential for personalized nutrition strategies
Gut microbial metabolism of L-carnitine, leading to the production of trimethylamine N-oxide (TMAO), links red meat consumption to cardiovascular risks. Microbial genes, including cntA/B, the cai operon, and the gbu gene ...
Jan 23, 2025
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Excess intestinal protein responsible for food allergy in children, study finds
When is food simply nourishing and enjoyable, and when does it provoke an allergic reaction? The answer appears to lie in the balance of microbes that live in our intestine—and a specific protein secreted by intestinal ...
Jan 22, 2025
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Biomarker algorithm for Barrett's esophagus and esophageal cancer developed
By studying biomarkers known to be involved in gastrointestinal cancers, researchers at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a biomarker algorithm that, ...
Jan 22, 2025
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Microbiome signatures can predict nonalcoholic fatty liver disease with high accuracy
Nonalcoholic fatty liver disease (NAFLD) affects up to 40% of the population in western countries and is one of the most common metabolic diseases worldwide. It is characterized by an excessive storage of fat in the liver ...
Jan 21, 2025
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Clinical trial finds no benefit from aspirin in preventing colorectal cancer recurrence
A new international clinical trial led by the National Cancer Center Singapore is reporting that three years of aspirin following standard adjuvant therapy for high-risk Dukes' B and C colorectal cancer did not yield a significant ...
We know what you ate: Detailed protein activity maps assess intestinal health
If the organs in our bodies could talk, the intestines might be the ones to divulge the most hidden truths about our lifestyle and health. Along the way, their "confessions" could supply crucial information for biomedical ...
Jan 20, 2025
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Inflammation may explain stomach problems in psoriasis sufferers
People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for "leaky gut," according to new research at Uppsala University. These changes in the gut could ...
Jan 20, 2025
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Rotavirus protein NSP4 manipulates calcium signaling, affecting disease outcomes
Researchers at Baylor College of Medicine and collaborating institutions have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick. The study published ...
Jan 18, 2025
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Unique characteristics of a rare liver cancer identified as clinical trial of new treatment begins
Like many rare diseases, fibrolamellar hepatocellular carcinoma (FLC) mounts a ferocious attack against an unlucky few—in this case, children, adolescents, and young adults. Because its symptoms can vary from person to ...
Jan 18, 2025
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New animal model offers insights into pancreatic disease and diabetes
Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication. A recent study published in eGastroenterology ...
Jan 17, 2025
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FDA approves Omvoh for moderately to severely active Crohn's disease
The U.S. Food and Drug Administration has approved Eli Lilly's Omvoh (mirikizumab-mrkz) for the treatment of moderately to severely active Crohn's disease in adults.
Jan 17, 2025
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Clinical trial advances research in treatment of biliary tract cancers
The results of a clinical trial led by researchers at the University of Arizona Health Sciences and published in the Journal of Clinical Oncology show that chemotherapy combining three different types of drugs did not improve ...
Jan 17, 2025
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Wearable devices detect and predict inflammatory bowel disease flare-ups
Wearable devices can identify, differentiate, and predict flare-ups, or the worsening of symptoms and inflammation, in inflammatory bowel disease (IBD), Mount Sinai researchers have shown in a first-of-its-kind study.
Jan 16, 2025
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Fatal neurodegenerative disease in kids also affects the bowel—gene therapy may help
Researchers at Washington University School of Medicine in St. Louis have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest ...
Jan 15, 2025
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Gluten-free food affordability a struggle for nearly half of Canadian households with kids who have celiac disease
Almost half of Canadian households that have children with celiac disease are struggling to afford gluten-free foods, according to a new study led by the University of Alberta published in the Journal of Pediatric Gastroenterology ...
Jan 14, 2025
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