TNF inhibitors prevent complications in kids with Crohn's disease: Study recommends them as first-line therapies
Early treatment of pediatric Crohn's disease with anti-tumor necrosis factor medications can substantially reduce the risk of perianal fistulas, a particularly debilitating complication of Crohn's disease.
Dec 23, 2024
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Upadacitinib found to improve ulcerative colitis outcomes at 12 months
For patients with ulcerative colitis, upadacitinib is associated with improved disease-specific outcomes at 12 months compared with tofacitinib, according to a study published in the December issue of the American Journal ...
Dec 23, 2024
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Coronary artery disease common in patients with cirrhosis
Coronary artery disease (CAD) is common in patients with cirrhosis, but cirrhosis itself is not significantly associated with an increased CAD risk, according to a review published online Nov. 21 in the Journal of Clinical ...
Dec 22, 2024
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Commercial tea bags release millions of microplastics, entering human intestinal cells
UAB research has characterized in detail how polymer-based commercial tea bags release millions of nanoplastics and microplastics when infused. The study shows for the first time the capacity of these particles to be absorbed ...
Dec 20, 2024
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Discovery of norovirus replication hubs offers new antiviral targets
Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no approved vaccines or ...
Dec 20, 2024
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Potential culprit identified in lingering Crohn's disease symptoms
A study by University of Michigan researchers may provide an explanation for why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation.
Dec 20, 2024
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Early detection model for pancreatic necrosis improves patient outcomes
A new prediction model for infected pancreatic necrosis (IPN) in patients with acute pancreatitis (AP) offers a groundbreaking approach to improving patient outcomes. Developed by a team of researchers across eight Chinese ...
Dec 20, 2024
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Chronic gut infection could play a role in Alzheimer's development
Arizona State University and Banner Alzheimer's Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's ...
Dec 19, 2024
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Shiitake-derived functional food shows suppression of liver fibrosis progression
Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during hepatitis, often resulting ...
Dec 19, 2024
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Diarrheal diseases remain a leading killer for children under 5, adults 70+
A global study reports a 60% drop in global mortality from diarrheal diseases, but children and the elderly still have the highest death rates, particularly in sub-Saharan Africa and South Asia. That's according to the latest ...
Dec 19, 2024
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Researchers identify key driver of fibrosis in Crohn's disease
Crohn's disease, a type of chronic inflammatory bowel disease (IBD), often causes scar-like tissue to build up in the intestines, termed fibrosis. Over time, increased scar tissue builds up in the intestinal walls, causing ...
Dec 18, 2024
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Probiotics with protective armor could boost gut health
A research team has developed a new method for encapsulating probiotics. They used nanoparticles formed by antisolvent precipitation to protect the probiotics, and tested the probiotics in lab simulations and animal experiments ...
Dec 18, 2024
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Oncologist discusses treating liver cancer
Liver cancer rates have more than tripled in the U.S. since 1980 and continue to rise. More than 41,000 people will be diagnosed with liver cancer in the U.S. this year, and about 29,000 will die from the disease, according ...
Dec 18, 2024
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Intestinal tuft cell expression changes with sleeping and eating cycles
A team of researchers from Carnegie Mellon University's Department of Biological Sciences and the University of Texas Southwestern Medical Center have uncovered how a subset of cells in the intestines change throughout the ...
Dec 17, 2024
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Flavonoids in polyphenols: Activating gut hormones to improve health
Polyphenols are a diverse group of compounds that contribute to the flavor and health benefits of foods like green tea, berries, and dark chocolate. Among these compounds, flavonoids—responsible for the vibrant colors in ...
Dec 17, 2024
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Researchers find previously unknown links between microbial bile acids and the risk of colon cancer
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk—in opposite ...
Dec 16, 2024
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C. elegans study reveals hidden mechanism of swallowing
A research team led by Professor Kim Kyuhyung at the Department of Brain Sciences, DGIST, has discovered a new principle that regulates how food moves through the digestive tract and is swallowed. They found that the Piezo ...
Dec 16, 2024
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Electrical stimulation of ears shows promise for treating ulcerative colitis
A simple, non-invasive treatment focused on the ears could one day provide relief for people with ulcerative colitis, a UM research study has found.
Dec 16, 2024
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Call for targeted strategies to combat gastric cancer cause
Addressing poor management of a preventable cause of gastric cancer will lead to better outcomes and improve equity and justice in health care, a group of health professionals argues.
Dec 16, 2024
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Early-onset colorectal cancer cases are surging, global study finds
A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster ...
Dec 12, 2024
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Dual screening in diabetes: Liver fibrosis and eye disease detection
New research from Karolinska Institutet in Sweden highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye disease.
Dec 12, 2024
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Scientists find promising new target for antidepressants—in the gut
Researchers have discovered new connections between the gut and brain that hold promise for more targeted treatments for depression and anxiety, and could help prevent digestive issues in children by limiting the transmission ...
Dec 12, 2024
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Unlocking the clock: The role of the circadian system in inflammatory bowel diseases
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are marked by cycles of immune activation and inflammation that significantly impact patients' lives.
Dec 12, 2024
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